A comparative study of 0.5% hyperbaric Ropivacaine versus 0.5% hyperbaric Bupivacaine for spinal anaesthesia
Journal Title: International Journal of Biomedical and Advance Research - Year 2016, Vol 7, Issue 6
Abstract
Aims and Objective: Aim of the present study was to compare the clinical efficacy of 0.5% hyperbaric solutions of ropivacaine versus bupivacaine in terms of characteristics of spinal blockade, haemodynamic stability, recovery profile and side effects. Material and Method: The study enrolling 100 patients (age 20-60 years) of either sex, ASA grade I & II were randomly allocated in two groups. Group R received 3 ml of 0.5% hyperbaric ropivacaine with glucose 8.33% and Group B received 3 ml of 0.5% hyperbaric bupivacaine with glucose 8%. After induction, we studied the various parameters of subarachnoid block, hemodynamic variables, recovery and side effects. Result: Hyperbaric ropivacaine had late onset of sensory blockade, equal time to reach maximum dermatome level, early regression and shorter total duration of sensory blockade as compared to bupivacaine. Ropivacaine shows late onset of motor blockade, less degree and total duration of motor blockade as compared to bupivacaine. Ropivacaine was more hemodynamically stable as compared to bupivacaine. Both the sensory and motor blocks were subject to a more rapid recovery with ropivacaine compared with bupivacaine. Hyperbaric ropivacaine was not associated with any side effects intra and postoperatively. Conclusion: 3 ml of hyperbaric solution of ropivacaine 0.5% with glucose 8.33% can produce predictable and reliable spinal anaesthesia for a wide range of surgical procedure.
Authors and Affiliations
Leena Ingale, Sheetal Dalal, Santosh Ingale, Naresh G. Tirpude, A. S. Tarkase, Manik C Gedam
Keywords
Related Articles
- EP ID EP364664
- DOI 10.7439/ijbar.v7i6.3419
- Views 87
- Downloads 0
Anticancer potential of aqueous extract of Mikania glomerata against H292 human lung cancer cell line
Herbal medicine is the oldest form of healthcare known to the human race with a history of documentation for almost 4000 years. The Mikania glomerata Sprengel, popularly known as 'guaco', have a long standing record of a...
A study of pattern of secretion of salivary melatonin in shift workers
Background: Globalization and industrialization lead round the clock service providers (shift workers) vulnerable for circadian rhythm sleep disorders Aim & Objective: To know how effect of shift work on secretory patter...
Comparison of three different methods to detect the production of ?-lactamase enzyme by staphylococci
Production ?-lactamase enzyme is the most common and important mode of exhibiting resistance to ?-lactam antibiotics. Manifestation of this enzyme is difficult to demonstrate in routine antibiotic sensitivity testing. Se...
Analytical study of treatment outcome of various topical modalities in Acne Vulgaris
Acne vulgaris is a multifactorial disease affecting the pilosebaceous follicle characterized by comedones, papules, pustules, nodules, cysts and scars. This study constituted 120 patients and was conducted at Department...
Evaluation of thyroid profile status in women with abnormal uterine bleeding in north Indian population
Background: Abnormal Uterine Bleeding is a common complication occurs in 9 14% of women from Menarche to Menopause. Women are more prone to thyroid disorder and cause abnormal sexual development, menstrual irregularity,...