A Comparative Study of 0.5% Levobupivacaine with Dexmedetomidine 50 MCG and 0.5% Levobupivacaine Plain in Supraclavicular Brachial Plexus Block
Journal Title: Indian Journal of Anesthesia and Analgesia - Year 2017, Vol 4, Issue 4
Abstract
Context: Several adjuncts are added to local anaesthetic agents to prolong the duration of regional blockade. In this study, we added dexmedetomidine to levobupivacaine for supraclavicular brachial plexus blocks. Aim: To compare the effectiveness of 50 mcg dexmedetomidine added to 0.5% levobupivacaine in supraclavicular brachial plexus block for upper limb surgeries with respect to onset and duration of motor and sensory blockade. Settings and Design: We conducted a randomized double blinded controlled trial on 40 patients, undergoing supraclavicular block. Methods and Material: Group A (n=20) received 30 ml of 0.5% levobupivacaine with 0.5 ml of normal saline and Group B (n=20) received 30 ml of 0.5% levobupivacaine with 0.5 ml of dexmedetomidine (50mcgs/0.5ml). Time of onset, completion and duration were noted for both sensory and motor blockade. Statistical Analysis Used: Chisquare test and student ttest and p value <0.05 was considered as significant. Results: Onset of motor and sensory blockade was significantly shorter with Group B (0.5% levobupivacaine with dexmedetomidine). The mean duration of sensory and motor blockade was significantly prolonged with 591± 30min. and 543±32min respectively. The mean sedation score was 2.60±0.503 (patients were sedated and arousable to verbal or mild physical stimulus) in Group B whereas the score was 1 (fully awake) in Group A. All patients were hemodynamically stable. Conclusion: We conclude that addition of dexmedetomidine 50mcgs to 0.5% levobupivacaine fastens the onset and prolongs the duration of motor and sensory blockade and provides good intraoperative sedation
Authors and Affiliations
G. Anandhakumar
Keywords
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- EP ID EP472298
- DOI 10.21088/ijaa.2349.8471.4417.13
- Views 102
- Downloads 0
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