A Comparative Study of Analgesia with Ropivacaine and Dexmedetomidine vs Ropivacaine and Fentanyl in Epidural Anesthesia in Lower Limb Surgeries
Journal Title: Indian Journal of Anesthesia and Analgesia - Year 2019, Vol 6, Issue 4
Abstract
Background: The popular techniques of regional anesthesia used for surgeries of lower limbs are Subarachnoid block is better term anesthesia and epidural anesthesia. Limitations of intrathecal anesthesia are short duration of analgesia, onset of sympathetic blockade rapidly and brief postoperative analgesia duration. Aim: To evaluate the synergistic effect of addition of dexmedetomidine to ropivacaine 0.75% and fentanyl to ropivacaine .75% in epidural anesthesia for surgeries of lower limbs. Materials and Methods: The study conducted in Gandhi hospital during period between December 2016 to November 2017. Institutional ethical committee clearance as well as informed consent from all patients was obtained from all patients. One hundred patients, who had various elective lower limb surgical procedures belonging to ASA class I and II were included in the study. Group RD (n = 50)–15 ml of 0.75% ropivacaine + 1.0 µg/kg of dexmedetomidine, Group RF (n=50) 15 ml of 0.75% ropivacaine and Fentanyl 1 µg/kg. Results: The mean time of onset of sensory blockade in group RD is 5.26 ± 1.49 mins and in RF 10.04 ± 2.5 mins. There is highly statistical significant difference between the groups (p = 0.000). The mean time taken for the onset of motor blockade is 11.22 ± 2.61 mins in group RD and 15.36 ± 3.28 mins in group RF There is statistical significant difference between the groups (p = 0.000). There is no statistically significant difference in the mean heart rate, mean systolic blood pressure, diastolic blood pressure and mean arterial pressure between groups at various intervals. Bradycardia and dry mouth seen only in the RD group none was in RF group. Hypotension, nausea and vomiting, tremors observed in both groups on comparision were stastically insignificant. Conclusion: Dexmedetomidine can be used as a more potent and safer alternative to Fentanyl in epidural anesthesia as a adjuvant to ropivacaine.
Authors and Affiliations
Burra Ramesh Kumar
Keywords
Related Articles
- EP ID EP668017
- DOI 10.21088/ijaa.2349.8471.6419.37
- Views 102
- Downloads 0
Comparative Study of Intrathecal Bupivacaine 0.5% with Midazolam 2mg and Bupivacaine 0.5% with Clonidine 50 µg for Postoperative Analgesia in Infra-Umbilical Surgeries
Background: Spinal anaesthesia is safe, reliable and inexpensive technique of providing surgical anaesthesia. The intrathecal use of clonidine is shown to be effective and safe. Several studies indicate that clonidine ex...
Efficacy of Laryngoscopy and Haemodynamic Response to Endotracheal Intubation: A Comparitive Study between Airtraq Optical Laryngoscope and Macintosh Laryngoscope
Background: Laryngoscopy and endotracheal intubation plays a crucial role in administering general anaesthesia. Laryngoscopes ranging from simple rigid scope with light bulb to complex...
A Comparative Study of Intrathecal Dexmedetomidine with 0.5% Bupivacaine and 0.5% Bupivacaine with Placebo in Lower Abdominal Surgeries
Introduction: Spinal anaesthesia represents an attractive proposition for daycase anaesthesia, being associated with less postoperative nausea and vomiting (PONV) and better postoperative pain relief than general anaesth...
Supraclavicular Versus Infraclavicular Approach of Subclavian Vein Cannulation in ICU Patients
Background: Subclavian vein is generally preferred in ICU for central venous access. Infraclavicular and supraclavicular approaches are the two techniques of subclavian venous catheterisation. Infraclavicular approach to...
Study of Dexmedetomidine as an Adjuvant to Local Anesthetics in Peribulbar Block for Cataract Surgery
Background: Many studies show that, Dexmedetomidine hastens the onset of sensory and motor block, prolongs anaesthesia and analgesia of local anesthetics in various neural blocks. Very few studies are done using Dexmedet...