A COMPARATIVE STUDY OF ATTENUATION OF STRESS RESPONSE DURING INTUBATION WITH ESMOLOL AND PROPOFOL
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2018, Vol 5, Issue 2
Abstract
BACKGROUND Endotracheal intubation for giving anaesthesia and for other purposes have become integral part of anaesthesiology. Tracheal intubation provides a patent airway for unconscious person. For endotracheal intubation, direct laryngoscopy is a tool. Direct laryngoscopy and passage of endotracheal tube are noxious stimuli that can provoke adverse responses in cardiovascular system. To prevent adverse responses different drugs are used in different methods. In the present study, we are comparing the effects of esmolol and propofol to obtund adverse responses in the cardiovascular system. MATERIALS AND METHODS Hospital-based prospective randomised comparative study, which includes 70 normotensive patients aged 15 to 60 years of either sex belonging to ASA I and II, Mallampati class 1 and 2 posted for various elective non-cardiac surgeries. In this study, the group 1 patients received esmolol 1 mg/kg bolus and in group 2 propofol 1 mg/kg bolus after 1 minute of induction. Haemodynamic parameters were recorded (SBP, DBP, MAP and HR) before and after intubation and compared. RESULTS The mean heart rate in both group 1 and 2 reduced significantly from preoperative value after 2 minutes of drug administration. The mean values of the haemodynamic parameters HR, SBP, DBP and MAP were compared in group 1 and 2 after 5 minutes of intubation. There is no statistically significance between the two groups as the p value >0.05. CONCLUSION Both esmolol and propofol were effective in attenuation of haemodynamic response to laryngoscopy and intubation.
Authors and Affiliations
Vallem Balasubramanyam, Sowmya G, Sai Suraj K. N, Talisetti Jamuna
Keywords
Related Articles
- EP ID EP448614
- DOI 10.18410/jebmh/2018/33
- Views 61
- Downloads 0
PREVALENCE OF THYROID DISORDERS IN PREGNANCY AT A TEACHING HOSPITAL
BACKGROUND Thyroid disorders are the second most common endocrinological disorders seen in pregnant women. Thyroid hormone plays a crucial role in pregnancy both in the development of a healthy baby and in maintaining th...
A RARE CASE REPORT ON NASAL CAVITY PARAGANGLIOMA
Paragangliomas are rare neuroendocrine neoplasm of extra adrenal autonomic nervous system. These are usually benign, slow growing vascular tumors found in the abdomen, thorax, head and neck region. Head and neck paragang...
ROLE OF ULTRASOUND IN MANAGEMENT OF BLUNT ABDOMINAL TRAUMA
BACKGROUND Blunt abdominal trauma is one of the most common causes of death in young population. It is a diagnostic challenge, even to the experienced surgeons. Timely management is very important to prevent death due to...
A CLINICAL COMPARATIVE STUDY OF ANALGESIC EFFECT OF TRAMADOL AND PENTAZOCINE IN POST-OPERATIVE PATIENTS FOLLOWING UPPER ABDOMINAL SURGERY
The post-operative pain can be treated by various approaches. Aim of this randomised prospective study was to compare two drugs (Tramadol and Pentazocine). 100 adult patients of both sexes of ASA status 1 & 2 posted for...
A COMPARATIVE STUDY OF EFFICACY OF PLAIN ROPIVACAINE WITH ROPIVACAINE AND CLONIDINE FOR POSTOPERATIVE CAUDAL ANALGESIA IN PAEDIATRIC PATIENTS
AIM: To evaluate the efficacy of plain ropivacaine 0.25% with that of ropivacaine 0.25% and clonidine 2µg/kg for post-operative analgesia caudally in paediatric patients undergoing subumblical surgeries. MATERIALS AND ME...