A comparative study of brachial plexus block using bupivacaine with midazolam and bupivacaine alone in upper limb surgeries
Journal Title: International Archives of Integrated Medicine - Year 2016, Vol 3, Issue 11
Abstract
Background: Adjuncts to local anaesthetics for brachial plexus block may enhance the quality and duration of analgesia. Midazolam, a water-soluble benzodiazepine, is known to produce antinociception and enhance the effect of local anaesthetics when given epidurally or intrathecally. Aim: Study was to assess the effect of Midazolam added to brachial plexus block by supraclavicular approach. Materials and methods: A prospective, randomized, single blinded study was conducted on 100 ASA Grade I or II adult patients undergoing upper limb surgeries under supraclavicular brachial plexus block. Patients were randomly divided into two groups. Patients in Group B (n = 50) Bupivacaine and Group BM (n = 50) Bupivacaine with Midazolam. The onset time and duration of sensory and motor blockade were recorded. Hemodynamic variables (i.e., heart rate, blood pressure and oxygen saturation), sedation scores and rescue analgesic requirements were recorded for 24 hour postoperatively. Results: The onset of sensory and motor block was significantly faster in Group BM compared to Group B (p < 0.05). The duration of sensory and motor block was significantly longer in Group BM compared to Group B (p < 0.05). Rescue analgesic requirements were significantly less in Group BM compared to Group B (p < 0.05). Hemodynamics and sedation scores did not differ between the two groups in the post-operative period. Conclusion: Midazolam (0.05 mg/kg) in combination with 30 mL of Bupivacaine (0.375%) hastened onset of sensory and motor block, and improved postoperative analgesia when used in brachial plexus block, without producing any adverse events.
Authors and Affiliations
Anil Kumar Akkenapalli, GV Sasidhar
Keywords
Related Articles
- EP ID EP505113
- DOI -
- Views 131
- Downloads 0
Patients’ Satisfaction with Diagnostic MRI Services in Teaching Tertiary Care Hospital in Telangana
Introduction: The health care industry is undergoing transformation to meet the demands of the patients. Hospitals are shifting from viewing patients as illiterates and with little health care choice, to that of educated...
A study of abnormal hematological parameters in dengue fever
Introduction: Dengue fever epidemics pose a serious issue of public health in India. Early clinical features of dengue infection are variable among patients, and initial symptoms are often non-specific resembling any vir...
Ketamine and levobupivacaine versus levobupivacaine alone for post operative analgesia and side effects in lower abdominal surgeries in children – A comparative study
Background: Different additive drugs such as opioids, epinephrine, clonidine, and neostigmine have been used along with local anaesthetics to improve the duration and quality of analgesia. Few studies have demonstrated t...
Impact of visual impairment on day-to-day visual functioning: A cross-sectional study among geriatric population in a rural area of West Bengal
Background: Visual impairment is a phenomenon which plagues many a human being be it of any age. It occurs all the more when the concern is the geriatric population. They seem to face many difficulties in their day-to-da...
Prevalence of symptomatic peptic ulcer in diabetes mellitus patients at out patient department of government medical college and hospital in and around villupuram district
Introduction: A peptic ulcer is a sore that forms when digestive juices wear away the lining of the digestive system. A peptic ulcer can occur in the lining of the stomach, duodenum, or lower part of the esophagus. Sympt...