A COMPARATIVE STUDY OF CELL BLOCK WITH CONVENTIONAL SMEAR CYTOLOGY IN DIAGNOSING SEROUS EFFUSIONS- A DESCRIPTIVE STUDY
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 6
Abstract
BACKGROUND Conventional cytology is the branch of pathology dealing in diagnosis of various fluids. But screening of remaining residue, which is not processed may be of paramount importance for diagnosis. The residual material may be evaluated by cell block preparation. Cell block study along with conventional smear cytology may improve the sensitivity of diagnosis. It is widely accepted that cellblock technique increases the cellular yield and improves diagnostic accuracy. The ability to obtain numerous tissue sections allows for multiple immunostains and other studies to be performed akin to paraffin sections produced in histopathology. Aims and objectives- The present study is undertaken to assess diagnostic efficacy of cell block preparation (CB) by combined approach of conventional smear (CS) cytology and cell block preparation in serous effusions. MATERIALS AND METHODS In this Descriptive study, material for both conventional cytology and cell blocks were collected simultaneously as per convenience. Total 98 samples were evaluated. Grading of cellularity, morphological preservation, architectural preservation and presence of background staining were compared. RESULTS Of the total 98 undergoing conventional cytological analyses, 74 (75.5 %) were reported as benign, 19 (19.3%) as malignant and 05 (5.10%) as suspicious of malignancy. With the cell block method, the results were 76 (77.55%) benign and 22 (22.44%) malignant. CONCLUSION Our study confirmed that the cell block method increases the diagnostic yield. Direct fluid smears and cell blocks complement each other, and our results indicate that both are needed in the diagnostic work-up of patients.
Authors and Affiliations
Ravi Singh, Sukhwant Singh Hayer, Vaibhav Pandurang Mane, Rupali Gopal Yelave, Vishrabdha Rahul Pawar
Keywords
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- EP ID EP399016
- DOI 10.14260/jemds/2018/175
- Views 84
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