A Comparative Study of Combined Spinal Epidural with Epidural for Labour Analgesia Using Lower Concentrations of Bupivacaine and Fentanyl

Journal Title: Indian Journal of Anesthesia and Analgesia - Year 2018, Vol 5, Issue 7

Abstract

Aim: 1. To compare the analgesic efficacy of combined spinal epidural with epidural for labour analgesia using lower concentrations of Bupivacaine and Fentanyl. 2. To asses the effects of these agents on the maternal physiology, progress and duration of labour, mode of delivery, foetal and neonatal outcome. Methods : A total of 40 labouring parturients of ASA 1 & 2 have been divided in to 2 groups (Epidural group & Combined Spinal Epidural group) with 20 in each group. Epidural group received 10 ml of 0.0625% Bupivacaine and 50 mcg of Fentanyl epiduraly as initial bolus, followed by intermittent epidural top ups of 7 ml of 0.0625% Bupivacaine and 2mcg/ml of Fentanyl every 1 hr. Combined Spinal Epidural group received 1.5 ml solution containing 0.625 mg of Bupivacaine and 25 mcg of Fentanyl intrathecally and followed 2 hrs later by intermittent top ups of 6 ml of 0.0625% Bupivacaine and 2mcg/ml of Fentanyl every 1 hr. Results : With respect to the onset and quality of analgesia in Epidural and CSE groups, there were statistically significant differences. Analgesic efficacy was compared in terms of Time of first painless contraction, Time of loss of sensation to pin prick, visual analogue pain scales during first and second stage, Episiotomy pain relief and global assessment of quality of analgesia. CSE group showed statistically significant differences in terms of onset and quality of analgesia. No significant variations in duration and mode of delivery, maternal side effects and neonatal outcome. Conclusion: CSE when compared to plain Epidural produced statistically significant pain relief and the side effects produced by combining Fentanyl and Bupivacaine on maternal power, passage and passenger were minimal, proving that the CSE is a safer and good alternative to epidural or labour analgesia.

Authors and Affiliations

M. R. Karthikeyan

Keywords

Related Articles

Sevoflurane Induction of Anaesthesia in Critically ill Patients Undergoing Emergency Laparotomy

Sevoflurane has characteristics of rapid inhalational induction of anaesthesia in 60 secs while maintaining spontaneous respiration, bronchodilatation, haemodynamic stability with rapid recovery in elective scenario. Thi...

Evaluation of Newborns by Normal Deliveries and Cesarean Sections under General Anesthesia by Application of Scanlon’s Scoring System

Background: In the present scenario there is an increased demand by the mothers for painless deliveries. Therefore the number of babies delivered by C Sections has increased. However it also necessitates one to study the...

Comparison of Modified Mallampati Test and Upper Lip Bite Test in Prediction of Difficult Endotracheal Intubation: A Prospective Study

Introduction: Unanticipated difficult laryngoscopic tracheal intubation accounts for a significant proportion of adverse anaesthetic outcome in clinical practice. Hence, it is important to identify patients with difficul...

Comparison of Point-of-Care versus Central Laboratory Measurement of Electrolyte Concentration in Intensive Care Patient

Background: Electrolyte values are measured both by arterial blood gas (ABG) analyzers and central laboratory autoanalyzers (AA), but a significant time gap exists between the availability of both these results, with the...

A Comparative Study of Epidural Dexmedetomidine and Clonidine as Adjuvant to 0.2% Isobaric Ropivacaine for Post Operative Analgesia in Lower Limb Orthopaedic Surgeries

Background: Various adjuvants are being used with local anesthetics for prolongation of analgesia like opioids, but the onset and duration of analgesia is improved when a local anesthetic is combined with alpha2 adrenerg...

Download PDF file
  • EP ID EP533883
  • DOI 10.21088/ijaa.2349.8471.5718.11
  • Views 66
  • Downloads 0

How To Cite

M. R. Karthikeyan (2018). A Comparative Study of Combined Spinal Epidural with Epidural for Labour Analgesia Using Lower Concentrations of Bupivacaine and Fentanyl. Indian Journal of Anesthesia and Analgesia, 5(7), 1151-1158. https://europub.co.uk/articles/-A-533883