A comparative study of dexmedetomidine and nalbuphine as an adjuvant to bupivacaine in lower limb surgeries done under epidural anaesthesia
Journal Title: Medpulse International Journal of Anesthesiology - Year 2017, Vol 3, Issue 1
Aims and Objectives: To compare the clinical profile of Nalbuphine and Dexmedetomidine as an adjuvant to Bupivacaine when administered epidurally with respect to sensory and motor blockade, level of sedation and duration of analgesia. Material and Methods: A study was carried out in the Department of Anaesthesiology of Indira Gandhi Government Medical College and Hospital, Nagpur from Nov 2014 to October 2016. The study included 70 adult patients undergoing infraumbilical and lower limb surgeries in epidural anaesthesia. Assessment of motor blockade was done with Modified Bromage Scale. Degree of pain was evaluated by Visual Analogue Scale. Level of Sedation was assessed by Five Point Scale. Result: There was statistically significant difference between the groups for onset of sensory block, duration of analgesia and reversal of motor blockade. The onset of motor blockade, time to achieve maximum sensory and motor blockade, sedation score, Visual analogue scale score were comparable between the groups. Conclusion: Dexmedetomidine is a better adjuvant to Bupivacaine for epidural anaesthesia when compared to Nalbuphine as it provides earlier onset of sensory blockade, prolonged duration of sensory block and postoperative analgesia with stable vitals and minimal side effects.
Authors and Affiliations
Sonali M Khobragade, Jagdish Kalbhor, Ruchi Saran, Sandhya Manjrekar, Soma Cham
Background: Carbon dioxide is the most commonly used gas to induce pneumoperitoneum during laparoscopic surgeries, as CO2 levels in blood and expiratory gas can be easily measured and monitored. However, insufflations of...
Background: worldwide WHO estimated that over 600 million people with a case of symptoms of tonsillitis occur annually i.e. 30% of world populations are effected by symptoms of tonsillitis In India it is estimated that a...
A randomised clinical trial to compare the butorphanol and nalbuphine as adjuvants in ultrasound guided supraclavicular brachial plexus block
Background: Supraclavicular brachial plexus block provides complete anaesthesia for surgeries of upper limbs especially below the mid humerus.Using ultrasound for blocks not only increases the success rate but also reduc...
Comparison between intravenous dexmedetomidine and esmolol for induced hypotension during functional endoscopic sinus surgery and modified radical mastoidectomy
Aim: Bleeding is one of the major problems during surgery which reduces operative field visibility and recognition of anatomical landmarks becomes quite difficult. We aim to compare Dexmedetomidine and esmolol for contro...
Comparative study of intrathecal bupivacaine and clonidine combination versus bupivacaine and dexmedetomedine for gynaecological procedures
Background: Gynaecological procedures are often done under regional anaesthesia.Various adjuvants are being used with local anesthetics for prolongation of intraoperative and post-operative analgesia. Dexmedetomidine, a...
How To Cite
Sonali M Khobragade, Jagdish Kalbhor, Ruchi Saran, Sandhya Manjrekar, Soma Cham (2017). A comparative study of dexmedetomidine and nalbuphine as an adjuvant to bupivacaine in lower limb surgeries done under epidural anaesthesia. Medpulse International Journal of Anesthesiology, 3(1), 35-42. https://europub.co.uk/articles/-A-260426