A Comparative Study of Dinoprostone Gel and Dinoprostone Pessary in Induction of Labour
Journal Title: Scholars International Journal of Obstetrics and Gynecology - Year 2018, Vol 1, Issue 5
Abstract
Induced labour is one in which pregnancy is terminated artificially, any time after foetal viability is attained, by a method that aims to secure vaginal delivery. At term, upto 15 – 30% of pregnancies in obstetrics practice are induced for labour due to various foetal and maternal indications. Dinoprostone (Prostaglandin E2 or PGE2) has been shown to be the most effective agent achieving for cervical ripening. The present study is conducted with an aim of comparison between the two preparations i.e. dinoprostone vaginal gel vs dinoprostone vaginal pessary administration in a pregnant women with singleton pregnancy with vertex presentation for efficacy and safety in induction of labour. This tertiary level hospital base prospective observational study is done on 100 pregnant women out of which 50 pregnant women were given dinoprostone vaginal gel and 50 pregnant women were given dinoprostone vaginal pessary after obtaining informed consent. Data were collected on number of doses of drug required for delivery (58% required single dose in gel group vs 80% required single dose in pessary group), need of oxytocin augmentation for delivery (56% in gel group vs 30% in pessary group), induction to delivery interval (Mean 20.86 Hrs in gel group vs 16.88 Hrs in pessary group), mode of delivery (Vaginal delivery 46% in gel group vs 80% in pessary group), maternal complication (84% in gel group vs 90% in pessary group with no complication) for maternal outcome and for foetal outcome liquor characteristic (72% in gel group vs 88% in pessary group with clear liquor) and NICU admission (12% in gel group vs 6% in pessary group). Dinoprostone vaginal pessary is more effective for cervical ripening in induction of labour then dinoprostone vaginal gel.
Authors and Affiliations
Dr. Nabanita Deka Mazumdar, Dr. Chandana Ray Das, Dr. Rupa Das
Keywords
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