A COMPARATIVE STUDY OF EFFICACY OF INRATHECAL ROPIVACAINE 0.5% (PLAIN) VERSUS BUPIVACAINE 0.5% (PLAIN)
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2014, Vol 1, Issue 16
Abstract
Bupivacaine is the most commonly used drug for spinal anesthesia. Ropivacaine is a relatively new enantomerically pure isomer of bupivacaine with a low pKa and low lipid solubility as well as less cardiotoxicity with a possibility of shorter duration of sensory as well as motor block compared to bupivacaine. The shorter duration of block could be helpful in early ambulation and early discharge particularly in day care settings. AIMS AND OBJECTIVES: The aim of the study were to evaluate the onset and duration of sensory and motor block, the maximum height of sensory block as well as the degree of motor block and haemodynamic stability of ropivacaine in comparision with bupivacaine. METHODS AND MATERIALS: Eighty ASA I or II patients undergoing lower abdominal and lower limb surgeries were randomly divided into two groups, Group R(n=40) revceived 3ml (15mg)of isobaric ropivacaine intrathecally and Group B(n=40) received isobaric bupivacaine 3ml(15mg) intrathecally. The onset and duration of sensory and motor block, height of sensory block and degree of motor block and haemodynamic stability were noted. RESULTS: Onset of sensory block and motor block were similar in both the groups. Onset time of sensory block in group R was 7.49±3.o5min and in group B was 6.75±2.01min (p value 0.2). Onset of motor block in group R was 2.23±1.63min and in group B was 2.27±1.34 min(pvalue0.16). The highest level of sensory block (T4) obtained in group R was n=3(7.5%), and in group B n=8(20%) (p<0.01) The duration of sensory block in group R was 181.93±46.87min and in group B was 247±51.77min (pvalue<0.001). The duration of motor block in group R was 158.49±42.7min and in group B was 222±48.53min (p<0.001). The degree of motor block was complete in both groups. There was no significant difference in haemodynamic stability between the groups. CONCLUSION: Intrathecal isobaric ropivacaine 15mg is similar to isobaric bupivacaine 15mg with respect to onset of sensory and motor block as well as degree of motor block. However a shorter duration of both sensory and motor block was seen in ropivacaine group compared to bupivacaine group.
Authors and Affiliations
Suma K. V, Udaya Bhaskar K.
Keywords
Related Articles
- EP ID EP227636
- DOI 10.18410/jebmh/2014/296
- Views 86
- Downloads 0
ANKYLOSING SPONDYLITIS: OPHTHALMOLOGIST PLAYS A MAJOR CRUCIAL ROLE!
BACKGROUND Ankylosing spondylitis (AS) is a chronic inflammatory systemic disorder affecting the axial skeleton with chronic pain and stiffness in the lower back or buttocks region and progressive limitation of spinal mo...
THE PREVALENCE OF ALCOHOL USE PROBLEMS AMONG AUTORICKSHAW DRIVERS IN RURAL KERALA- FINDINGS FROM A COMMUNITY-BASED PILOT STUDY
BACKGROUND Alcohol Use Disorders (AUD) form a major public health concern especially in a developing country like India. Alcohol is implicated in a wide variety of diseases, disorders and injuries and a multitude of soci...
MYOCARDIAL BRIDGES AND CORONARY DOMINANCE
BACKGROUND Myocardial bridges are bands of cardiac muscle fibers, which bridges across the coronary arteries and its main branches. It is considered as a congenital anatomical variant mainly seen across the left anterior...
LATE PRESENTATION OF CONGENITAL DIAPHRAGMATIC HERNIA IN ADULTS: “OUR EXPERIENCE”
Congenital Diaphragmatic Hernia (CDH) usually presents with respiratory distress in the neonatal period. Late onset CDH is less common and is associated with a wide range of clinical symptoms. The authors report two case...
CLINICAL RELEVANCE OF COEXISTENCE OF DUCTAL CA IN SITU AND INVASIVE DUCTAL CARCINOMA OF BREAST
BACKGROUND There are many studies reported in the literature with respect to the Ductal Carcinoma in Situ (DCIS) progressing into Invasive Ductal Carcinoma (IDC) of the breast. However, there is hardly any study on the c...