A COMPARATIVE STUDY OF EFFICACY OF LOCAL INSULIN VERSUS TOPICAL PHENYTOIN IN DIABETIC FOOT ULCER
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2017, Vol 4, Issue 51
Abstract
BACKGROUND Diabetic foot ulcer is the common complication and it affects almost 15% of all diabetic patients. Majority of the ulcer can heal. Healing is better in neuropathic ulcer than neuroischaemic ulcer. In India, diabetic foot ulcer is common cause of nontraumatic amputation of limbs, which is preventable. MATERIALS AND METHODS It is an open labelled randomised prospective study conducted at Department of General Surgery, Konaseema Institute of Medical Sciences, Amalapuram. Total 90 patients divided randomly into three groups include this study as per exclusion and inclusion criteria. Group A were diabetic foot ulcer belongs to topical insulin dressing group. Group B belongs to topical phenytoin group and group C belongs to conventional wound care group. RESULTS In group A, size of the wound reduced from mean value 6.8 cm2 to 1.4 cm2 ; percentage change in the size of the wound was 79.4%. In group B, the size of the wound reduced from 5.9 cm2 to 2.4 cm2 ; percentage reduction in the size of the wound was 59.3%. In group C, the mean size of the wound was reduced from 7.1 cm2 to 4.2 cm2 ; percentage reduction was 40.8%. The depth of the wound also reduced in the entire three groups. Mean reduction in the depth of the wound in group A was 9 mm to 2 mm that is 77.7%. In group B, the percentage mean reduction was 69.0%, and in group C, it was 51.2%. CONCLUSION In present study, we have found that percentage change in the mean surface area of wound in insulin group is 79.4%. The percentage change in mean of wound surface area of wound in group B (phenytoin group) was 59.3%, which is less than insulin group. There was significant change in the depth of wound in both the group, but in insulin group, it is better than phenytoin group.
Authors and Affiliations
Sanjeev Rao M, Bhushan Kumar G. C, Anand Acharya
Keywords
Related Articles
- EP ID EP220253
- DOI 10.18410/jebmh/2017/623
- Views 90
- Downloads 0
A RARE PRESENTATION OF GIANT CELL TUMOUR OF DISTAL ULNAWIDE RESECTION AND RECONSTRUCTION USING PROXIMAL FIBULA AND TFCC RECONSTRUCTION USING PALMARIS LONGUS TENDON
Giant cell tumour of the bone (GCT) is a rare locally aggressive primary bone tumour with an incidence of 3% to 5% of all primary bone tumours. The most common location for this tumour is the long bone meta-epiphysis esp...
EFFICACY OF ACTIVATION PROCEDURES TO ILLUSTRATE EEG CHANGES IN EPILEPSY
BACKGROUND EEG or Electroencephalogram, which is the most important diagnostic procedure to evaluate Epilepsy patients, may sometimes fall short of accurate sensitivity and may require few Activation Procedures such as ‘...
USE AND CHOICE OF TOOTHPASTE BY MOTHERS OF PRESCHOOL CHILDREN IN KASHMIR, (JAMMU AND KASHMIR), INDIA
BACKGROUND A variety of toothpastes are available in the market, however proper knowledge and choice of fluoride toothpastes to be used is important in children for better oral health care. Parents especially mothers sho...
A RARE CASE OF MASSIVE OMENTAL CYST MIMICKING AS AN OVARIAN CYST
A 15 yr old girl presented with distension of abdomen & anorexia of 6months duration. On examination there was massive distension of abdomen, and a vague cystic mass with fluid thrill. A diagnosis of ascites / ovarian ma...
A CROSS-SECTIONAL DESCRIPTIVE STUDY ON SUICIDAL ATTEMPTS AT A TERTIARY CARE INSTITUTION
BACKGROUND Suicides and suicidal attempts are increasingly recognized as growing public health problems globally. World Health Organization observes that the prevalence, characteristics and methods of suicidal behaviour...