A Comparative Study Of Efficacy of Silodosin With Or Without Tadalafil In Treatment of Lower Urinary Tract Symptoms Associated With Bph (LUTS/BPH) In Men – A Single Centre Study
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2019, Vol 4, Issue 6
Abstract
Background: Benign prostatic hyperplasia (BPH) is a histologic diagnosis that refers to the proliferation of smooth muscle and epithelial cells within the prostatic transition zone. Aim of this study was compare the efficacy of silodosin with or without tadalafil in treatment of lower urinary tract symptoms associated with BPH (LUTS/BPH) in men. Methods: A total of 120 patients who fulfill the inclusion criteria were recruited into the study, which is approved by the hospital ethical committee of our hospital and study was conducted from August 2016 to December 2017. Full informed written consent was obtained from each eligible patient before enrolment.Results:IPSS evaluated before initiation of treatment at 0 week, and re-evaluated after 4 week and after six week follow up in all cases. The means of IPSS in both groups were found comparable before initiation of treatment. The differences in means of IPSS were statistically not different in both groups after four weeks and six weeks follow up.Conclusion: In our study, results showed that the combination of Silodosin and Tadalafil significantly improving (reducing) LUTS when compared with alpha blocker (silodosin) monotherapy.
Authors and Affiliations
Rupam Kumari
Keywords
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