A Comparative Study of Intrathecal Dexmedetomidine and Fentanyl as an Adjuvant to Bupivacaine
Journal Title: Journal of Medical Science And clinical Research - Year 2015, Vol 3, Issue 12
Abstract
In recent years, the use of intrathecal adjuvants has gained popularity. The quality of spinal anaesthesia is improved with addition of opioids and other drugs but no drug is without side effects. The aim of this study was to compare the addition of either Dexmedetomidine or Fentanyl to intrathecal Bupivacaine as regards the onset and duration of sensory and motor block, hemodynamic effects, postoperative analgesia and adverse effects of either drug. Sixty patients with ASA grade I and II scheduled for lower limb and lower abdominal surgeries were randomly allocated to two groups (30 patients each): Group D received 2.5 ml 0.5% hyperbaric Bupivacaine and 5 µg of Dexmedetomidine intrathecally. Group F received 2.5 ml 0.5% hyperbaric Bupivacaine and 25 µg of Fentanyl intrathecally. Patients in group F had faster onset of motor and sensory block than group D (P = 0.000). Patients in group D had significantly longer duration of motor and sensory blockade as compared to those in group F (P = 0.000). Postoperative analgesia was significantly longer in group D than group F (P =0.000). Incidence of side effects among the two groups was not statistically significant. Fentanyl has faster onset compared with Dexmedetomidine but prolonged duration of sensory and motor blockade with postoperative analgesia was seen with Dexmedetomidine without significant side effects.
Authors and Affiliations
Dr Rashmi Bengali
Keywords
Related Articles
- EP ID EP213065
- DOI -
- Views 71
- Downloads 0
Efficacy of Autologous Serum Therapy in Patients with Recalcitrant Chronic Urticaria and Positive Autologous Serum Skin Test
Background: Chronic urticaria (CU) is a common problem and negatively affects both work and social life because of its chronic relapsing course and poor response to therapy. Conventional therapies of CU sometimes fail to...
A Retrospective Study on Ceaserean Section in Semi Urban AreasIndications
Caeserean Section is a common operative procedure in obstetric practice throughout the world to ensure a healthy outcome of the mother and new-born. The advent of modern anesthesia, antibiotics and availability of blood...
Chart for Sudanese Fetal Age Assessment using Sonographic Fetal Limb Bones Measurements
A study conducted on140pregnant women referred routinely for routine scan of 14 – 40 weeks’ gestation at ultrasound department of Oma-algora specialize hospital (Aljazeera-Sudan) during the period from June 2016 to Febru...
Study of the Baseline Widal Titres among Healthy Population in a Tertiary Care Hospital in Central India
Background: In developing countries like India, Enteric fever is endemic. Widal agglutination test is used for its diagnosis. In a single serum sample the only test frequently relied upon for laboratory diagnosis is Wida...
Effect of Glycemic Control on Radiographic Presntation of Pulmonary Tuberculosis in Type 2 Diabetes Mellitus
Introduction: Tuberculosis (TB) remains to be a major cause of morbidity and mortality throughout the world. The link of Diabetes (DM) and TB is more prominent in developing countries and the higher susceptibility of tub...