A Comparative Study of Intrathecal Fentanyl and Dexmedetomidine as Adjuvants to Bupivacaine
Journal Title: International Journal of Contemporary Medical Research - Year 2016, Vol 3, Issue 1
Abstract
Introduction: Spinal anaesthesia is the most preferred regional anaesthesia technique. Present study was done to study the efficacy of Intrathecal Fentanyl and Dexmedetomidine with 0.5% heavy Bupivacaine for infra umbilical surgeries. Materials and Methods: 100 patients belonging to ASA physical status I & II of both sexes were devided into two groups of 50 each. Group F received 3ml Inj.0.5% Bupivacaine heavy with 25 micrograms of Fentanyl and Group D received 3ml Inj 0.5%. Bupivacaine heavy with 5 micrograms ofDexmedetomidine. The time of onset of sensory and motor block, haemodynamic status, duration of analgesia and adverse effects if any were compared in both the groups. Results: Time from injection to highest sensory level and Onset of Bromage 3 was similar in both groups. Time from injection to T10 sensory level was significantly shorter in Group D (p<0.001), and Time for regression to Bromage 0 was significantly longer in group D (p<0.001). Intraoperatively both groups remained haemodynamically stable. Incidence of bradycardia was more in Group D and incidence of pruritus was more in Group F though it was not statistically significant (p=0.402). Intraoperative sedation was higher in Group D (p<0.001) and post operatively Visual analogue scores were significantly lower with group D (p<0.001) Conclusion: Dexmedetomidine appears to be an attractive adjuvant to intrathecal bupivacaine than Fentanyl as there is significantly longer duration of motor block, additional benefits of intraoperative sedation and decreased analgesic requirement in the post-operative period.
Authors and Affiliations
K. Sunil Kumar, G. Bharathi, R. Pandu Naik, B. Srinivas Rao
Keywords
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