A comparative study of intravenous hydralazine versus labetalol in the management of severe hypertension in pregnancy
Journal Title: The New Indian Journal of OBGYN - Year 2017, Vol 4, Issue 1
Abstract
Objective: The objective of this study is to compare the efficacy as well as safety profile of hydralazine and labetalol in severe hypertension of pregnancy. Methodology: Hundred (100) women with severe pregnancy induced hypertension were randomly allocated into two groups of 50 each. Study group was given intravenous hydralazine and control group was treated with labetalol. The efficacy of two drugs were noted in terms of time taken to achieve target blood pressure, number of doses required and number of patients developing severe persistent hypertension. Results: The average time taken to control blood pressure (BP) in hydralazine group was 32.66 ± 18.79 minutes and 30.70 ± 20.46 minutes in labetalol group and this was statistically significant (p<0.001).There was no statistical difference between the two drugs in terms of efficacy, perinatal outcome and adverse affect except headache which was significantly more in hydralazine group. Conclusion: Both hydralazine and labetalol can be used to treat hypertensive emergencies.
Authors and Affiliations
Shruti Singh, Swati Kochar, Santosh Khajotia, Suman Budania, Dr Anjana
Keywords
Related Articles
- EP ID EP452405
- DOI 10.21276/obgyn.2017.4.1.5
- Views 136
- Downloads 0
Role of drainage in surgical repair of vesicovaginal fistula
none
Rupture uterus incidence and management in a tertiary centre in Assam
Objectives: The purpose of this study was to see the incidence of rupture uterus, the predisposing factors and the different modalities of management with outcome. Methodology: All patients of rupture uterus admitted dur...
Maternal and neonatal outcome in patients with vaginal birth after cesarean section (VBAC)
Objective: The aim of study is to know the maternal and fetal outcome in the present pregnancy of patients with previous one caesarian section (CS). Methodology: A prospective study was undertaken to know the neonatal an...
A retrospective study of maternal and fetal outcome of viral hepatitis in pregnancy
Objectives: This study was conducted to evaluate the cause, course of the condition in pregnancy, maternal and fetal outcome in diagnosed cases of viral hepatitis in pregnancy. Methodology: A retrospective study was cond...
Ectopic vaginal ureterocele presenting as vaginal gartner’s cyst
Ureterocele represent the intramural portion of distal ureter. Most of them are associated with the upper moiety ureter of a duplex system and are therefore ectopic and are commonly inserted within the bladder neck. A 23...