A comparative study of Olopatadine and Ketorolac eye drop with Ketorolac eye drop alone in seasonal allergic conjunctivitis
Journal Title: International Journal of Medical Research and Review - Year 2017, Vol 5, Issue 9
Abstract
Background: Seasonal allergic conjunctivitis is the most common allergic disorder seen in eyes. The aim of study was to compare the clinical efficacy of combination of 0.4% ketorolac and 0.1% olopatadine with 0.4% ketorolac alone in seasonal allergic conjunctivitis. Material and Method: The study was prospective, double blind parallel group comparative. Two hundred cases enrolled in the study. All the subjects were randomly divided in two groups, 100 in each. Group 1 patients received 0.4% ketorolac eye drop in both eyes 2 times a day and group 2 patients received combination of 0.1% olopatadine and 0.4% ketorolac in both eyes 2 times a day. Observations were collected at baseline and on day 3,7,15 and analyzed statistically regarding improvement in sign and symptoms. Result: In group 1, 50- 60% patients had no sign and symptoms on day 15 whereas in group 2 more than 95% patients showed improvement in clinical picture. p value was significant (p<0.0001) at day 15 in all sign and symptoms and on day 3 in itching and on day 7 in watering. Overall group 2 patients had better and earlier response regarding symptoms of itching at day 3. Conclusion: The combination of 0.1% olopatadine and 0.4% ketorolac was more effective than 0.4% ketorolac alone in seasonal allergic conjunctivitis patients.
Authors and Affiliations
Ravindra Kumar Meena, M. L. Gupta, H. P. Sharma
Keywords
Related Articles
- EP ID EP274346
- DOI 10.17511/ijmrr. 2017.i09.01
- Views 116
- Downloads 0
Study of the effect of intrathecal dexmedetomidine as an adjuvant in spinal anesthesia for Gynecological Surgery
Background: A randomized controlled study was designed to investigate the effects of addition of dexmetomedine to hyperbaric bupivacaine 0.5% for spinal anaesthesia in patients undergoing gynaecological surgeries, in ter...
Missed a beat: Is it your Ayurvedic drug?
24 year male presented with watery diarrhoea, 10-15 episodes/day since 2 days, vomiting, abdominal pain and giddiness since 1 day. Patient was hypotensive and had bradycardia. Rest of systemic examination was normal. ECG...
A clinical study of prevalence of ocular manifestations in malnourished children attending Anganwadi centers in urban slum areas
Aim: A clinical study of prevalence of ocular manifestations in malnourished children attending anganwadi centers in urban slum areas. Material & Method: A cross sectional study was carried out in Anganwadi centers of ur...
A cadaveric study on accessory lobes of lungs and their bronchial branching pattern
Background: An accessory lobe is a part of lung tissue separated off by an accessory fissure. It develops due to occasional monopodial branching of the stem bronchi. Different accessory lobes may be encountered in the hu...
Role of fine needle aspiration cytology in assessment of cervical lymphadenopathy
Background: Lymphadenopathy is one of the commonest clinical presentations of patients attending the outdoor department. The causes vary from simple treatable infections to malignancies and hence need to be speedily inve...