A COMPARATIVE STUDY OF ORAL OLANZAPINE AND ORAL HALOPERIDOL ON GLUCOSE TOLERANCE LEVELS IN PATIENTS WITH SCHIZOPHRENIA
Journal Title: International Journal of Medical Research & Health Sciences (IJMRHS) - Year 2015, Vol 4, Issue 3
Abstract
Background: Schizophrenia is a mental disorder characterized by persistent defects in the perception, thinking or the expression of reality. The term "schizophrenia" translates roughly as "shattered mind," and comes from the Greek (schizo, "to split" or "to divide") and (phrēn, "mind"). Material and Methods: The study was designed to be a prospective control study. Schizophrenic patients taking Olanzapine and Haloperidol were selected and follow up at three weeks and six weeks was done. Results: In this prospective control study, Olanzapine and Haloperidol were associated with an increase in Blood Glucose Levels. The mean changes in Glucose remained within clinically normal range in this six week study. Conclusion: Antipsychotic treatmemt leads to the development of Diabetes mellitus in a significant 10.1% of patients within 6 weeks. Given the serious implications for morbidity and mortality attributable to diabetes mellitus, clinicians need to be aware of these risk factors when treating patients with chronic schizophrenia.
Authors and Affiliations
G N S Sangeetha Lakshmi| Asst Professor, Dept of Pharmacology, Osmania University, Hyderabad, Corresponding author email: asangeethalakshmi@yahoo.co.in
Keywords
Related Articles
- EP ID EP11426
- DOI 10.5958/2319-5886.2015.00092.2
- Views 301
- Downloads 12
An anatomical study on the variations of short saphenous vein and its termination
The short saphenous vein represents the post axial vein of developing limb bud. It is the continuation of lateral marginal vein. The short saphenous vein terminates in the popliteal vein in the popliteal fossa. Short sa...
Pros and Cons of student marriage during study period among student in Yasuj University of Medical science, Iran
Because the student course is also the age and period of marriage and moreover the students are facing the important task of education which necessitates subjective and mental tranquility therefore the present research...
PONTIAC FEVER ASSOCIATED WITH ERYTHEMA NODOSUM
Legionellae are gram-negative bacteria found in clean water sources worldwide. Infection with Legionella species presents as two distinct clinical forms; Legionnaires' Disease; characterized by pneumonia and Pontiac Fe...
A CROSS SECTIONAL STUDY OF THE MORBIDITY PATTERN AMONG THE ELDERLY PEOPLE : SOUTH INDIA
Background: In 1950, just 8% of the world population was aged 60 years or over, by 2005 that proportion had risen to 10% and it is expected to be more than double over the next 45 years, reaching 22% by 2050. Evaluatio...
Effect of Damask Rose Extract on FSH, LH and Testosterone Hormones in Rats
Damask rose is an herbal medicine that increases libido as recommended in traditional medicine. The present study aimed to evaluate the effect of damask rose extract on serum levels of sex hormones in male rats. In this...