A Comparative Study of Platelet Indices in Acute Coronary Syndrome
Journal Title: International Journal of Contemporary Medical Research - Year 2017, Vol 4, Issue 3
Abstract
Introduction: Platelet indices are simple and reliable indicators of emerging biomarkers of cardiovascular events and might potentially help in stratifying cardiovascular risk. Studying this correlation may help us in timely interventions. Study aimed to see the platelet indices in patients presenting with acute coronary syndromes and to study the association of platelet indices and the occurrence of acute coronary syndromes Material and methods: This was a comparative study conducted among three groups each consisting of 25 patients each with STEMI, NSTEMI and Non-Cardiac Chest Pain (NCCP) respectively. The platelet indices were analysed from the venous samples in an auto-analyser. Data were analyzed using SPSS version 16.0. The platelet indices among the three groups were analyzed by chi-square (categorical) and ANOVA (continuous) tests. A P value of < 0.05 was considered statistically significant. ROC curves were plotted to assess the predictive efficacy of these platelet indices in predicting acute coronary syndromes. Results: The platelet indices, the mean platelet volume, platelet distribution width and platelet large cell ratio were significantly higher in STEMI and NSTEMI groups when compared to the NCCP group. Conclusion: Patients with acute coronary syndromes had higher MPV when compared to NCCP group. Therefore measurement of platelet volume indices may be of help in differentiating the individuals with cardiac and non-cardiac chest pain and hence could benefit from early interventions.
Authors and Affiliations
Kruthika S Patil, S D Karchi
Keywords
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