A COMPARATIVE STUDY OF RETINAL NERVE FIBER LAYER THICKNESS IN NORMAL AND GLAUCOMATOUS EYES USING SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2018, Vol 5, Issue 11
Abstract
BACKGROUND Glaucoma is the leading cause of irreversible blindness in the world. The peripapillary Retinal Nerve Fiber Layer (RNFL) thickness evaluation is a useful method to detect the early structural damage of glaucoma. The purpose of present study is to assess and compare the Retinal Nerve Fiber Layer thickness in Primary Open Angle Glaucoma and control group using SD-OCT. MATERIALS AND METHODS 70 eyes with POAG and 70 normal eyes were included in the study. All subjects underwent basic workup for glaucoma including standard automated perimetry and optic nerve head evaluation using Cirrus SD-OCT. RESULTS Average RNFL thickness is significantly reduced in diagnosed cases compared to normal subjects .In POAG cases it is 58.19 ± 15.87µm and in normal subjects it is 91.91 ± 6.85µm (p<0.001). There is positive correlation between MD and average RNFL thickness and negative correlation between PSD and RNFL thickness. CD ratio has a negative correlation with RNFL thickness. CONCLUSION The result indicates that SD-OCT helps largely to detect and measure decrease in RNFL thickness in diagnosed glaucoma cases. So it is noteworthy in diagnosing glaucoma at an early stage consequently preventing further damage.
Authors and Affiliations
Saba Firdos Khan, Manoj Balke, Rohan Dhananjay Nalawade
Keywords
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