A comparative study of sensory-motor coordination, executive function, and testosterone levels in hypothyroid and euthyroid males
Journal Title: National Journal of Physiology, Pharmacy and Pharmacology - Year 2018, Vol 8, Issue 3
Abstract
Background: Hypothyroidism is an endocrine disorder that is seen much more commonly in females than in males. This could perhaps be due to factors that confer protection against the development of hypothyroidism in males. The male sex hormone testosterone would have protective action on the different systems, probably due to a mechanism of action which is complementary. Aims and Objective: To investigate the association between serum testosterone level, audiovisual reaction time, and working memory score in newly diagnosed hypothyroid and euthyroid men. Materials and Methods: This was a comparative study. 15 newly diagnosed hypothyroid males between 18 and 45 years of age, recruited from the Endocrinology Department of MS Ramaiah Medical College Hospital, Bangalore, and 15 euthyroid males were assessed for audiovisual reaction time, working memory, serum testosterone, T4, and serum thyroid hormones (TSH). Results: Independent t-test between hypothyroid and euthyroid groups revealed that there was statistically significant difference in group mean audio-visual reaction time, working memory, serum T4, and TSH levels (P < 0.05). Conclusion: Hypothyroid patients had longer audiovisual reaction time and the working memory scores were reduced. The serum T4 level was lower and serum TSH level was higher, but the serum testosterone level was not significantly different compared to euthyroid subjects
Authors and Affiliations
Joseph Ivin Thomas, Venkatesh D, Pramila Kalra
Keywords
Related Articles
- EP ID EP486950
- DOI 10.5455/njppp.2018.8.0833416102017
- Views 79
- Downloads 0
Hardness of tap water samples in Manila City, Philippines through complexometric titration
Background: Water hardness varies depending on the source, treatment procedures, and pipeline conditions among others, though not of immediate concern in water quality control but may have significant health, infrastruct...
Perceptions about normal physiological changes during adolescence and assessment of the impact made through an educational intervention program for adolescents in school children in a rural set up in Gujarat
Background: Adolescence is a period full of life marked by various changes such as biological, social, and psychological changes. Adolescence age group is particularly important seeing to the fact that this is a vibrant...
In vitro antibacterial potential of chitosan and its derivatives on pathogenic enterobacteriaceae
Background: Chitosan (deacetylated chitin) and its derivatives, which are known to possess pharmaceutical and biomedical properties, have gained considerable attention in the biomedical field. The nontoxic, biocom...
A rare cause of hypertension in a newborn: Adrenal hemorrhage
Adrenal hemorrhage due to birth trauma is a complication that can be seen in neonates. The most common symptoms are anemia, prolonged jaundice, and a palpable mass in the abdomen. It can rarely lead to hypertensio...
A randomized prospective comparative study of weight gain between asenapine and iloperidone in patients with psychosis
Background: Second-generation antipsychotics (SGAs) are better for psychotic disorders, and they can induce weight gain and other serious metabolic adverse effects which can lead to non-adherence and medical comorbiditie...