A comparative study of sensory-motor coordination, executive function, and testosterone levels in hypothyroid and euthyroid males
Journal Title: National Journal of Physiology, Pharmacy and Pharmacology - Year 2018, Vol 8, Issue 3
Abstract
Background: Hypothyroidism is an endocrine disorder that is seen much more commonly in females than in males. This could perhaps be due to factors that confer protection against the development of hypothyroidism in males. The male sex hormone testosterone would have protective action on the different systems, probably due to a mechanism of action which is complementary. Aims and Objective: To investigate the association between serum testosterone level, audiovisual reaction time, and working memory score in newly diagnosed hypothyroid and euthyroid men. Materials and Methods: This was a comparative study. 15 newly diagnosed hypothyroid males between 18 and 45 years of age, recruited from the Endocrinology Department of MS Ramaiah Medical College Hospital, Bangalore, and 15 euthyroid males were assessed for audiovisual reaction time, working memory, serum testosterone, T4, and serum thyroid hormones (TSH). Results: Independent t-test between hypothyroid and euthyroid groups revealed that there was statistically significant difference in group mean audio-visual reaction time, working memory, serum T4, and TSH levels (P < 0.05). Conclusion: Hypothyroid patients had longer audiovisual reaction time and the working memory scores were reduced. The serum T4 level was lower and serum TSH level was higher, but the serum testosterone level was not significantly different compared to euthyroid subjects
Authors and Affiliations
Joseph Ivin Thomas, Venkatesh D, Pramila Kalra
Keywords
Related Articles
- EP ID EP486950
- DOI 10.5455/njppp.2018.8.0833416102017
- Views 87
- Downloads 0
Waist-hip ratio and cardiac responses to exercise in young adults with parental history of coronary heart disease
Background: Coronary heart disease (CHD) has become a major health challenge in India in 21st century. Family history is a major risk factor for CHD which strongly predisposes to atherosclerotic process at a younger age....
Amphotericin B abolishes the cytotoxic effect of Toll-like receptor 9 agonist CpG Oligonucleotides in breast cancer cell line MCF-7
Background: Toll-like receptors (TLRs) are key sensors of microbial components and triggers signals responsible for the activation of innate immune responses. Unmethylated cytosine-guanosine oligodeoxynucleotides called...
Autonomic cardiovascular regulation in Parkinson’s disease by head-up tilt test - A cross-sectional study
Background: Autonomic failure is an integral component of Parkinson’s disease (PD), and orthostatic hypotension (OH) is commonly observed in advanced cases of PD. OH may be the result of underlying cardiovascular autonom...
Polydipsia: Comparative action of two antipsychotics – Pimozide and ziprasidone
Background: Primary polydipsia occurs without any central (vasopressin) deficit and/or peripheral (nephrogenic) organic impairment-associated with schizophrenia/obsessive compulsive disorder. In absence of associated sym...
Evaluation of lung function tests in rheumatoid arthritis patients
Background: Pulmonary manifestation is one of the most common extra-articular features in rheumatoid arthritis (RA) leading to significant morbidity. Lung function testing helps in identifying the type of respiratory def...