A Comparative Study of Sleep Disorders between Familial and Sporadic Parkinson’s Disease
Journal Title: International Journal of Neurology and Neurosurgery - Year 2017, Vol 9, Issue 2
Abstract
Background: Parkinson’s disease (PD) is associated with many nonmotor features including various types of sleep dysfunction. So, the present study was conducted to compare pattern and prevalence of sleep disturbances in sporadic and familial PD. Materials & Methods: The patients in present study were recruited from movement disorders clinic of tertiary teaching hospital after approval from the institution ethics committee and written informed consent from all patients. Patients with comorbid illness likely to cause sleep dysfunction were excluded from the study. Familial and sporadic PD patients who participated in the study were interviewed using standardised questionnaires using Parkinson’s Disease Sleep Scale (PDSS) and Epworth Sleepiness Scale (ESS). All patients underwent Polysomnography (PSG) using Biological Sleep Scan machine and results were evaluated with the help of a Qualified Sleep Specialist. Results: There was no significant difference with respect to PDSS total score and ESS total score between the two groups of PD. The overall prevalence of any sleep disturbance on PSG in Familial PD patients was 80% and it was 90% in Sporadic PD patients. There was no significant difference in the prevalence of Sleep disordered breathing, sleep fragmentation and periodic limb movements between the two groups. Conclusion: Sleep disturbances were common in both Familial and Sporadic PD patients in present study. No difference was found in overall nocturnal and daytime sleep symptomatology except less severe nocturnal akinesia and morning dystonia in Familial group.
Authors and Affiliations
Anis Jukkarwala
Keywords
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- EP ID EP466985
- DOI 10.21088/ijnns.0975.0223.9217.3
- Views 93
- Downloads 0
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