A Comparative Study of ‘Sterile Water’ Versus ‘Glycine (1.5%)’ As Irrigation Fluid in Transurethral Resection of Prostate
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 5
Abstract
Aims and Objectives: The present research study was carried out with an objective to study and compare the effects of Sterile Water versus Glycine (1.5%) as an irrigation fluid in surgery of ‘Trans-Urethral Resection of Prostate (TURP). Methods: This was a prospective randomized double blind study. A total of 60 patients of (Age: 50-80 years) ASA grade I and II with Benign Prostatic Hyperplasia posted for trans-urethral resection of prostate were randomly allocated in two equal groups as Group W- Sterile Water group and Group GGlycine1.5% group. The observations in relation to intra-operative haemo-dynamics, haemoglobin, blood urea, serum creatinine and serum electrolyte changes were noted and analyzed. Results: Statistically there were similar changes in heart rate, systolic and diastolic blood pressures during the procedure in both the groups. Immediately after surgery and after 24 hrs, the comparable changes were seen in both the groups in relation to haemoglobin, blood urea and serum creatinine levels. Post-operative serum sodium concentration was decreased and serum potassium concentration was increased significantly in both groups. These changes in serum sodium & potassium were more so in Group W as compared to in Group G; but the difference in two groups was statistically insignificant. Incidence of perioperative complications was comparable amongst the groups. Conclusion: As compared to Glycine (1.5%), Sterile Water was found to be safe and inexpensive irrigation fluid for ‘Trans-Urethral Resection of Prostate’ (TURP). In relation to safety profile, we did not find any difference between two irrigation fluids. As our sample size of study was small, needs further similar studies on large sample size to confirm the observations of present study
Authors and Affiliations
Dr Kshitija Kulshreshtha
Keywords
Related Articles
- EP ID EP285269
- DOI -
- Views 69
- Downloads 0
Assessment of Allergic Rhinitis in North Indian Population
Allergic rhinitis is typically triggered by environmental allergens such as pollen, pet hair, dust, or mold. Inherited genetics and environmental exposures contribute to the development of allergies. Growing up on a farm...
A Pharmacoepidemiological Study Of Ticagrelor & Current Antiplatelet Agents In Acute Coronary Syndrome (ACS) & Percutaneous Transluminal Coronary Angioplasty (PTCA)
The incidence of ACS is rapidly increasing in India & causing high mortality. In the treatment pattern of ACS & PTCA, antiplatelet agents are prescribed as a part of maintenance & prophylactic therapy. Ticagrelor, a newe...
Impact of various teaching tools on learning in Pharmacology: a crosssectional study among second year M.B.B.S students
Background: Our study aims to assess and compare the impact of teaching tools like chalk and talk method and power point presentation on different areas of learning in pharmacology. Methods: This cross sectional question...
Reconstruction of ankylosed Proximal Interphalangeal Joint of a Finger Using Conchal Cartilage
Ankylosis of Proximal Interphalangeal Joint (PIPJ)of a finger can occur after intra-articular fractures, burns, degenerative conditions likerheumatoid arthritis. Not only are fingers with ankylosed PIP joints of little u...
Comparison of Colour Doppler Flow Imaging with Voiding Cystourethrography in the Detection of Vesicoureteric Reflux in Children
Introduction: Early detection and management of Vesicoureteric reflux (VUR) prevents the adverse renal effects. Voiding cystourethrography (VCUG) is considered the gold standard for diagnosis of VUR. Colour Doppler flow...