A Comparative Study of the block Characteristics of Intrathecal 0.5 Bupivacaine with and without Fentanyl as Adjuvant in Patients Undergoing Transurethral Resection of Prostate
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 11
Abstract
Background: Spinal anaesthesia is a regional technique that blocks the spinal nerves in the subarachnoid space. The anaesthetic agents that are deposited subarachnoid space act on the spinal nerve roots. It is extensively used for genitourinary surgeries like transurethral resection of prostate, transurethral resection of bladder tumours, cystoscopy, gynaecological and obsteteric procedures, abdominal surgeries, orthopaedic procedures etc. This study is designed to evaluate the block characteristics of intrathecal hyperbaric bupivacaine with and without fentanyl as adjuvant in patients undergoing TURP. Objective: To study the block characteristics of intrathecal hyperbaric bupivacaine with and without fentanyl as adjuvant in patients undergoing TURP, as assessed by time to 2 segment regression of sensory blockade ,time to regression of sensory block level to L1, time to first rescue analgesic, duration of motor blockade,and the maximum motor block produced, in patients undergoing TURP. Methodology: 40 Patients undergoing transurethral resection of prostate (TURP) belonging to American Society of Anaesthesiologists Physical Status (ASA) grade 1 and 2 were enrolled in this study after getting informed consent and institutional ethical board clearance and randomly allocated into two groups. Group ‘1’ received 7.5mg 0.5% heavy Bupivacaine (1.5ml) with 25µg Fentanyl (0.5ml)- total of 2ml, while group ‘2’ received 7.5mg 0.5% heavy Bupivacaine (1.5ml) with 0.5ml sterile water (total 2ml) . Results: It was found from this study that Group ‘1’ prolongs the duration of sensory block (91.8±5.3 min) compared to Group ‘2’(75.7±4.9 min),provides longer duration of postoperative analgesia,227.5±24min in Group’1’compared to 183.2±8.6min in Group ‘2’ and causes a delay in the attainment of peak sensory levels 7.4±1.0 min in Group ‘1’ compared to 6.3±0.7 min in Group’2’, without affecting the peak sensory block, maximum motor block or duration of motor block.
Authors and Affiliations
Dr Harikrishnan. S
Contribution by Surgical Oncologist in Palliating Cancer Patients - Retrospective analysis at Acharya Harihar Regional Cancer Centre, Cuttack, India
A total of 583 cancer patients needing emergency surgical intervention treated in the surgical oncology department during period of 5 years and 10 months from April 2011 to January 2017 at Acharya Harihar Regional Cancer...
A Clinicopathological Study and Management of Diabetes Skin Ulcers – An Institutional Experience
Background: Diabetes is a worldwide problem. A good number of diabetic patients develop wound in one point of time or other during the course of their illness. The etiopathogenesis of diabetic lesions are multifactorial....
Review of Blood Transfusion Reactions in a Tertiary Hospital Blood Bank
Background: Transfusion of blood components are vital therapeutic procedures in clinical medicine. However patients may still be at risk of adverse effects of transfusions. Analysis of all untoward effects of blood trans...
Follow Up With Clinical Characteristics and Somatic Growth in Posterior Urethral Valve
Purpose- Follow up of PUV patients is very crucial. We analyzed the long term follow up in posterior urethral valves with clinical characteristics and somatic growth. Materials and methods- Study has been carried out bot...
A Case Series of 10 Patients with Trachonychia (20 Nail Dystrophy)
Background: Trachyonychia can be a manifestation of a pleomorphic group of disorders or can be idiopathic. The aim of this study to evaluated the clinico- epidemiological characteristics of trachonychia and possible etio...