A Comparative Study of Widal Test and Typhidot in Rapid Diagnosis of Typhoid Fever
Journal Title: International Journal of Medical Research Professionals - Year 2017, Vol 3, Issue 2
Abstract
Background: Typhoid fever is a major public health problem and a leading cause of morbidity and mortality globally. It is usually diagnosed by conventional methods like Blood culture and Widal test. Typhidot is a rapid and reliable serological test for diagnosis of typhoid fever. The aim of the present study was to evaluate the utility of Typhidot test in rapid diagnosis of typhoid fever in terms of sensitivity and specificity. Materials and Methods: The study group included 85 clinically suspected typhoid fever cases of all age groups and both sexes. Blood culture, Widal test and Typhidot test were performed on all the patients. Widal and Typhidot tests were compared for sensitivity and specificity. Results: Out of total 85 clinically diagnosed typhoid fever cases enrolled in the study, 11 cases (13%) were positive by blood culture, 20 (23.5%) by Widal test and 22 (26%) by Typhidot test. Widal test has a sensitivity of 54%, specificity of 81%, positive predictive value of 30% and negative predictive value of 92% in comparison with blood culture results. Typhidot test has a sensitivity of 91%, specificity of 84%, positive predictive value of 45% and negative predictive value of 98% in comparison with blood culture results. Conclusion: Typhidot test is a rapid, easy to perform and a reliable diagnostic test and can be useful in early institution of therapy.
Authors and Affiliations
Neha Garg
Keywords
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- EP ID EP543731
- DOI 10.21276/ijmrp.2017.3.2.017
- Views 75
- Downloads 0
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