A Comparative Study to Assess the Effectiveness of using Air, a 50% N2 O:O2 and Lignocaine 2% to Inflate the Endotracheal Tube Cuff During General Anaesthesia
Journal Title: International Journal of Contemporary Medical Research - Year 2017, Vol 4, Issue 3
Abstract
Introduction: Endotracheal tube (ETT) is one of the most frequently used mode for administering general anesthesia at the time of surgeries and it provides an artificial channel through which the inhalational anesthetic agents like halothane, isoflurane, sevoflurane, nitrous oxide(N2 O) can be delivered to the lungs. An ETT cuff when inflated with either Air, N2 O, saline, lignocaine during general anaesthesia will have complications like emergence phenomenon and post-operative sore throat. Study objectives were to find out the most effective intra-cuff inflating agent among air, a 50% gaseous mixture of N2 O: O2 and 2% lignocaine and to assess post-operative sore throat pain in each group. Material and methods: The present study was a comparative study carried out in adult patients who underwent surgeries under general anaesthesia during Oct 2014-May16. Study was done in KMC Attavar hospital and KMC hospital Jyothi circle, Mangalore and District government Wenlock hospital, Mangalore. For comparison of cuff pressures, with an α error of 5%, β error of 20% and mean difference in pressure of 10cm H2 0 and variance of 15cmH2 0, the sample size was 105 with 35 subjects in each armGroup A (Air), Group N (N2 O: O2 ) and Group L (lignocaine). Randomization of the subjects into study groups was done after obtaining a written informed consent and the study has been approved by Institutional Ethics committee. Results: Out of 105 study subjects, 59(56.2%) were found to be male and 46(43.8%) were found to be female. Mean age of the participants was 39.4±10.8 years. ANOVA test showed a significant difference in mean cuff pressures in three groups with air showing an increased cuff pressures, Group N showed decreased and L with stable pressures (p<0.001). Conclusion: The use of lignocaine 2% to inflate the endotracheal tube cuff provides stable intracuff pressure and reduces the incidence of sore throat pain when compared to air and a mixture of 50% N2 O:O2 .
Authors and Affiliations
Puneeth Nagarajaiah, Jesni Joseph Manissery, Thrivikram Shenoy, Usha Rani S Padmanabha
Keywords
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