A Comparative Study to Evaluate the Effects of Addition of Intrathecal Fentanyl with Clonidine To 0.5% Levo-Bupivacaine for Patients Undergoing LSCS.
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2019, Vol 4, Issue 6
Abstract
Aim: To evaluate the effects of fentanyl and Clonidine added to levo-bupivacaine, for caesarean section in spinal Anaesthesia 2. To evaluate the duration of analgesia by comparing two groups. 3. To evaluate the hemodynamic effects, post-operative sedation and neonatal outcome between the two groups. Materials and methods: Following approval by the institutions ethical committee, this prospective study was done at Dr SMCSI Medical College, Karakonam on 120 patients undergoing elective or emergency caesarean section after getting informed consent from each patient and explaining the procedure. This is a randomized prospective comparative study. Statistical Analysis: The Randomization of three groups was done by matching their age, height, and weight of their demographic factors and base Physiological factors such as pulse rate, SBP, respiration rate and SPO2 by ANOVA (Analysis of Variance). The differences between them were interpreted by the Post hoc test of Bonferroni. Similarly, the time for maximum loss of sensation, the 2 segment regression time, pain free time and Apgar score at 1 minute and 5 minutes were compared between groups by ANOVA. Conclusion: 1.Intrathecal clonidine and the clonidine fentanyl combination, both improved quality of Intra Operative analgesia 2. An amalgamation of clonidine and fentanyl accentuated the intra operative analgesic potency and remarkably lengthened the post-operative analgesia in comparison with just mere clonidine. 3. Stable Intra Operative hemodynamics was obtained. 4. Duration of analgesia was prolonged.
Authors and Affiliations
Dr Jemela Bennet
Keywords
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