A Comparisoin of Fentanyl Citrate and Magnesium Sulphate as Adjuvants to 0.5% heavy Bupivacaine in Spinal Anaesthesia
Journal Title: Indian Journal of Anesthesia and Analgesia - Year 2019, Vol 6, Issue 1
Abstract
Spinal anaesthesia is preferred regional anaesthesia technique in lower abdominal surgeries. Advantages are conscious and spontaneously breathing patient [25], good muscle relaxation, cost effectiveness and adjuvants injected intrathecally prolong the anaesthetic effects [26,27]. Aim of the study: To compare Fentanyl Citrate and Magnesium sulfate as adjuvants to 3 ml of 0.5% bupivacaine in infraumbilical surgeries under spinal anaesthesia, about onset and duration of sensory and motor block, intraoperative hemodynamics, postoperative pain and side effects. Materials & Methods: After Institutional ethics committee approval, a double-blinded comparative study was conducted in 100 patients at Osmania General hospital during 2014-2017. Patients were divided into two groups of 50 no.’s each Group F- 3 ml 0.5% Heavy Bupivacaine & Fentanyl citrate 25 mcg, Group M –3 ml 0.5% Heavy Bupivacaine & MgSO4 100 mg were deposited intrathecally. Intraoperatively Sensory and Motor block onset and duration, HR, SBP, DBP & MAP, SpO2, side effects were assessed. Results: In group M– onset of sensory and motor block is significantly prolonged , duration of analgesia, motor block is comparable to group F and patients in group M were hemodynamically stable perioperatively, and at end of 24 hrs postoperatively VAS score was ≥ 3 at indicates a quality post operative analgesia. Conclusion: Fentanyl citrate as adjuvant to 0.5% heavy bupivacaine effectively augmented quality of spinal anaesthesia; its advantages are limited by incidence of side effects. MgSO4 100 mg provides excellent perioperative analgesia and stable hemodynamics and is an attractive non-opioid adjuvant alternative to fentanyl.
Authors and Affiliations
Rajola Raghu
Keywords
Related Articles
- EP ID EP601176
- DOI 10.21088/ijaa.2349.8471.6119.45
- Views 66
- Downloads 0
Randomised Clinical Trial on Effect of Adding Magnesium Sulphate with 0.75% Ropivacaine and Dexmedetomidine with 0.75% Ropivacaine in Patients Undergoing Elective Laparotomy in a tertiary care hospital
Background: Laparotomies requires a good amount of pain relief postoperatively to avoid delay in recovery and reduce the duration of stay in the hospital. Among multiple modalities of pain relief postoperative wound infi...
Comparision of Bupivacaine with and without Clonidine as for Supraclavicular Approach to Brachial Plexus Block
Introduction: The role of peripheral nerve blockade was expanded for management of post operative pain and chronic pain. Tramadol and fentanyl had been successfully used as adjuvant to local anaesthetic in brachial plexu...
A Clinical Comparative Study between Caudal LevobupivacaineClonidine and Ropivacaine- Clonidine for Postoperative Analgesia in Paediatric Subumbilical Surgeries
Context: The use of clonidine as adjuvant to newer anaesthetic agents like levobupivacaine or ropivacaine in caudal block enhance postoperative analgesia. Aims: the purpose of the study was to compare the efficacy of lev...
A Study of Comparison of Intubating Conditions and Haemodynamic Effects after the Administration of Succinylcholine and Rocuronium Bromide
Background and Aim: Though rocuronium has a rapid onset of neuromuscular blockade like succinylcholine without the latter's adverse effects, its use is limited due to its prolonged action. Present study was performed wit...
Effect of Clonidine Given by Three Different Routes as Adjuvant to Bupivacaine in Spinal Anaesthesia
Context: Spinal anaesthesia is the most common method of regional anaesthesia used for lower limb and abdominal surgeries below umbilicus.There is always interest in finding adjuvants that prolong the duration of anaesth...