A COMPARITIVE EVALUATION OF 0.75% ROPIVACAINE WITH CLONIDINE AND 0.75% ROPIVACAINE WITH DEXMEDETOMIDINE IN SUPRACLAVICULAR BRACHIAL PLEXUS BLOCK- A PROSPECTIVE RANDOMISED DOUBLE-BLIND STUDY
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2018, Vol 5, Issue 2
Abstract
BACKGROUND Brachial plexus blockade is considered as cornerstone of regional anaesthesia practice. Ropivacaine is a new amide, long acting, pure S (-) enantiomer and local anaesthetic. This study was done to compare clonidine and dexmedetomidine as an adjuvant to 0.75% ropivacaine in supraclavicular brachial plexus block. MATERIALS AND METHODS A prospective randomised double-blind study was done in 80 patients of American Society of Anesthesiologist (ASA) grade I and II undergoing elective upper limb surgeries under supraclavicular block. Patients were randomised into 2 groups. Group 1 (n=40) received 30 mL of 0.75% ropivacaine with clonidine 1 mcg/kg and group 2 (n=40) received 30 mL of 0.75% ropivacaine with dexmedetomidine 1 mcg/kg. Onset and recovery time of sensory and motor block, duration of analgesia and quality of block, haemodynamic variables and level of sedation were studied in two groups. RESULTS Sensory and motor block onset times were shorter in group 2 (onset of sensory block was 4.9 ± 1.08 minutes and onset of motor block was 8.9 ± 1.41 minutes) than in group 1 (onset of sensory block was 10.7 ± 4.05 minutes and onset of motor block took 12.1 ± 4.11 minutes) (p value <0.0001). Sensory and motor block durations and duration of analgesia were longer in group 2 than in group 1 (p<0.0001). Blood pressure and heart rate were lower in group 2 as compared to group 1 (p value <0.0001). The number of patients achieving grade 4 quality of block was higher in group 2 as compared to group 1. CONCLUSION Dexmedetomidine (1 mcg/kg) hastens the onset of sensory and motor block, prolongs the duration of sensory and motor block, enhances the quality of block and sedation and also prolongs duration of analgesia as compared with clonidine (1 mcg/kg) when used as an adjuvant to 0.75% ropivacaine in supraclavicular block.
Authors and Affiliations
Vallem Balasubramanyam, Sai Suraj K. N, Talisetti Jamuna
Keywords
Related Articles
- EP ID EP448582
- DOI 10.18410/jebmh/2018/23
- Views 58
- Downloads 0
ASSESSMENT OF TTK CHITRA MITRAL PROSTHETIC VALVE AT REST AND EXERCISE BY ECHOCARDIOGRAPHY
BACKGROUND Assessment of prosthetic valve by echocardiography remains an important aspect in prosthetic valve follow up. Changes in transvalvular gradient during increase in heart rate (HR) is a common phenomenon. In thi...
PSYCHOSOCIAL EFFECTS OF TYPE 1 DIABETES MELLITUS IN CHILDREN
BACKGROUND The aim of the study is to assess the psychological and general scholastic performances of the children with type 1 diabetes. MATERIALS AND METHODS Study design is a hospital-based cross-sectional study. 42 ch...
EVALUATION OF GLYCATED ALBUMIN AND HbA1c LEVELS WITH BODY MASS INDEX IN POLYCYSTIC OVARIAN SYNDROME CASES
BACKGROUND Polycystic ovarian syndrome (PCOS) is a highly prevalent endocrine-metabolic disorder that implies various severe consequences to female health, including alarming rates of infertility. Although its exact aeti...
MULTIPLE MYELOMA: CLINICOHAEMATOLOGICAL STUDY OF 3 YEARS AT A TERTIARY CARE CENTRE
BACKGROUND Multiple myeloma is also called as plasma cell myeloma or myelomatosis. It is a malignant clonal proliferation of neoplastic plasma cells within the bone marrow. Its incidence increases with age. Multiple Myel...
ABDOMEN GROANS: A RARE CAUSE OF PANCREATITIS
Hyperparathyroidism and hypercalcaemia are considered to be a rare cause of acute pancreatitis. The relationship between hyperparathyroidism and pancreatic inflammatory disease remains controversial. (1) But it has been...