A Comprehensive Review on Antidiabetic Potential of Medicinal Plants
Journal Title: International Journal of Ayurveda and Pharmaceutical Chemistry - Year 2017, Vol 0, Issue 0
Abstract
Diabetes mellitus is one of the common metabolic disorders acquiring around 2.8% of the world's population and is anticipated to cross 5.4% by the year 2025. India is slated to be the diabetic capital of the world, with 50.8 million diabetics. Since ancient time plants have been exemplary source of medicine. Ayurveda and other Indian literature mentioned the used of plants in treatment of various ailments. Recently, the World Health Organization (WHO) recommended the use of medicinal plants for the management of DM and further encouraged the expansion of the frontiers of scientific evaluation of the hypoglycemic properties of diverse plant species. A comprehensive review was conducted to pile up information about medicinal plants used for the treatment of diabetes mellitus. The profiles presented include information about the scientific and family name, plant parts and test model used, the degree of hypoglycemic activity, and the active chemical constiutents. The review describes some new bioactive drugs and isolated compounds from plants such as diallyl trisulfide, lophenol, cinnamaldehyde, curcumin, mangiferin, oleanolic acid, coagulanolide, tetrahydrocurcumin showing significant insulinomimetic and antidiabetic activity with more efficacy than conventional hypoglycaemic agents. Thus, from the review majorly, the antidiabetic activity of medicinal plants is attributed to the presence of polyphenols, flavonoids, terpenoids, coumarins and other constituents which show reduction in blood glucose levels. The review also discusses the management aspect of diabetes mellitus using these plants and their active principles.
Authors and Affiliations
Vadi Ranjan, Manisha Vats
Keywords
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