A comprehensive review on Liposomes: a novel drug delivery system
Journal Title: Journal of Drug Delivery and Therapeutics - Year 2018, Vol 8, Issue 6
Abstract
Liposome was derived from two Greek words “Lipos meaning fat and Soma meaning body”. Liposome were spherical shaped vesicles consist of phospholipids and cholesterol. Due to their size hydrophobic and lipophilic character they are very promising system for drug delivery. This novel drug delivery system aims to target the drug directly to the site of action. Liposomes are very biocompatible and stable and have unique property to entrap both hydrophilic drug and lipophilic drug (amphiphatic nature) to its compartment and lead to controlled release effect. They are of 0.05- 5.0 micrometer in diameter. Liposomes are used for the treatment of various diseases like tumors or cancer. This article provides an overview of Liposomal Drug Delivery System and various aspects related to liposome that can be studied.
Authors and Affiliations
Keywords
Related Articles
- EP ID EP495390
- DOI 10.22270/jddt.v8i6.2071
- Views 85
- Downloads 0
GASTRO RETENTIVE NON-FLOATING DRUG DELIVERY APPROACH: A REVIEW
Gastro retardation is attractive approach to enhance bioavailability of narrow absorption window drugs. Drug retardation in stomach is more beneficial for certain gastro intestinal disorders like gastro esophageal reflex...
FORMULATION, EVALUATION AND OPTIMIZATION OF RANITIDINE HYDROCHLORIDE FLOATING TABLETS WITH IMPROVED GI ABSORPTION
Oral drug delivery system represents one of the main areas of sustained drug delivery system. Floating drug delivery system related to oral sustained drug delivery system group, which is capable of floating in the stomac...
PHYTOCHEMISTRY AND MEDICINAL USES OF MORINGA OLEIFERA: AN OVERVIEW
This paper review the retrospective studies on the Moringa oleifera at molecular level. There are about thirteen species of Moringa trees in the family Moringaceae. Moringa oleifera Lam. (synonym: Moringa pterygosperma G...
DEVELOPMENT AND VALIDATION OF BIOANALYTICAL RP HPLC METHOD FOR THE ESTIMATION OF METOPROLOL TARTRATE IN RABBIT PLASMA AFTER TRANSDERMAL AND ORAL ADMINISTRATION: APPLICATION IN PHARMACOKINETIC STUDIES
A simple, specific, sensitive and rapid Reverse phase high performance liquid chromatographic (RP-HPLC) method has been developed and validated for the quantification of Metoprolol Tartrate in small volumes of rabbit pla...
DISSOLUTION METHOD DEVELOPMENT WITH CHROMATOGRAPHIC METHOD FOR DETERMINATION OF DRUG RELEASE IN DISSOLUTION SAMPLES OF URSODEOXYCHOLIC ACID TABLETS.
Ursodeoxycholic Acid is used in the treatment of Liver disease. An accurate and robust invitro method is developed and validated for measurement of drug release in Ursodeoxycholic Acid tablets. HPLC method for quantifica...