A controlled study on the prevalence of underactive thyroid in type 2 diabetes
Journal Title: International Journal of Medical Science and Public Health - Year 2015, Vol 4, Issue 4
Abstract
Background: The term “thyroid diabetes” depicts the effect of excess thyroid hormones in the progressively worsening glucose control. Subclinical hypothyroidism is most commonly present in females than males, reaching a prevalence of up to 20% in older females. Hashimoto’s thyroiditis and Graves’ disease are the principal causes of hyper- and hypothyroidisms. Objectives: (1) To study the prevalence of hypothyroidism in diabetes and to evaluate the etiologic evidence of triglycerides on prevailing cardiovascular risk and metabolic syndrome. (2) To determine the mean levels of fasting blood sugar (FBS), HbA1c, triiodothyronine, serum thyroxin, and thyroid-stimulating hormone. (3) To evaluate the hemoglobin levels and to establish the prevalence of anemia in diabetic patients with hypothyroidism. (4) To determine the mean age and male/female ratio in diabetic patients with hypothyroidism. Materials and Methods: This study was a hospital-based case–control study carried out at Department of General Medicine, Owaisi Hospital and Research Center, Deccan College of Medical Sciences, Hyderabad, India. A total of 76 patients (63 women and 13 men) were enrolled in the study along with 38 control participants after explaining the study process and taking an inform consent. Blood samples were collected on the basis of history of diabetes noted for these patients. Results: Among 76 patients included in the study, 38 patients were having diabetes and hypothyroidism and the rest of them had normal diagnostic profile. The mean age was found to be 33.5 ± 13.8, and 18.5% men and 81.5% women were having hypothyroidism along with diabetes. The thyroid profile of patients with diabetes showed a remarkable increase in thyroid-stimulating hormone and this was considered to be the hypothyroidism as the mean level in the patients was 15.4 ± 17.1. Conclusion: In this study, diabetic patients with hypothyroidism showed increased FBS, HbA1c levels as the Hb levels were decreased whereas the triglyceride levels were increased from moderate to high, which in turn increased the susceptibility to cardiovascular risk and metabolic syndrome. Therefore, patients need timely cardiac monitoring and life style modification to avert the metabolic syndrome and cardiovascular risk
Authors and Affiliations
M Kaleemullah Khan, Mohd Nasir Mohiuddin
Keywords
Related Articles
- EP ID EP138026
- DOI http://dx.doi.org/10.5455/ijmsph.2015.0412201490
- Views 66
- Downloads 0
Bacterial colonization in patients with lower respiratory tract specimens: demographic profile and microbiological pattern
Background: Pseudomonas aeruginosa is an opportunistic human pathogen and is the predominant causative agent in nosocomial infections. Resistance to nearly all the available antibiotics has been shown by P. aerug...
Morphometric analyses of human dry tali of South Indian origin
Background: Talus is the key bone of the human body as it carries the whole weight of the body. Since the talus endures a lot of differential forces during locomotion, the stress patterns across the talus in fl uence...
Assessment of school absenteeism: A community-based study among children aged 7–18 years in a slum of Kolkata
Background: Education is one of the basic needs for human development and going to school regularly is crucially important for advancement of a student’s academic and social skills. Objectives: The main purpose of this s...
The prevalence of metabolic syndrome among chronic disease patients in Alwazarat health center at Prince Sultan Military Medical City, Riyadh, Saudi Arabia, 2014
Background: The presence of metabolic syndrome (MS) results in heart attacks twice the time in people with MS and in thrice the time the chances of experiencing a heart attack or stroke in those with MS when compared...
Study of H1N1 cases admitted at tertiary care hospital with special reference to neutrophil–lymphocyte ratio and lymphocyte–monocyte ratio as a screening tool for suspected H1N1
Background: Influenza A (H1N1) infection has been causing significant morbidity and mortality since 2009 epidemic all over the world. There needs to be rapid isolation of suspected patient to prevent further spread....