A Correlation between Glycosylated Haemoglobin & Lipid Profile in Type 2 Diabetes Mellitus with & Without Complications
Journal Title: Journal of Medical Science And clinical Research - Year 2015, Vol 3, Issue 2
Abstract
Objective: To determine whether the prevalence of dyslipidaemia & associated complications are associated with hyperglycaemia or poor glycaemic control. Methods: This was a prospective and analytical study. Type 2 diabetes mellitus patients who were attending the out patients clinic. 50 patients and 50 healthy subjects were included in the study. 50 clinically and biochemically confirmed cases of type 2 diabetes mellitus with and without complications of long duration, of both sexes and aged 35 to 75 years were selected. Results: The mean age of cases was 51.46±12.71 and 52.48±12.76 in controls. The FBS level was significantly (p=0.0001) higher among cases (122.26±68.39) compared with controls (79.28±11.84). The PPBS was also higher (p=0.0001) among cases (188.20±87.27) than controls (124.12±10.96). The level of HbA1C was higher among cases (7.47±1.90) compared with controls (5.48±0.41). The increased level of TC, TG, LDL and VLDL was observed among cases than controls (p<0.01). However, decreased level of HDL was found among cases compared with controls (p>0.05). Overall, 40% of the cases had any one of the complications. Conclusion: The rate of complications are higher in case of poor glycaemic control as compared to good glycaemic control in type 2 diabetes mellitus patients, thus, HbA1c can be used as a predictor of dyslipidemia in patients with type II diabetes in addition to its importance as glycemic control parameter.
Authors and Affiliations
Dr. Prabhakar Singh Bais
Keywords
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