A correlative study of salivary and plasma glucose levels in type 2 diabetic patients with and without complications
Journal Title: International Journal of Clinical Biochemistry and Research - Year 2016, Vol 3, Issue 2
Abstract
Introduction: There are contradictory reports on using salivary glucose in diagnosis of diabetes mellitus. This study has made an attempt to estimate the salivary glucose levels in diabetic patients with and without complications and correlate them with plasma glucose as a marker of type 2 diabetes mellitus. Method: This was a Cross sectional observational study. Thirty eight type 2 diabetic patients without complications and thirty eight type 2 diabetic patients with either microvascular or macrovascular complications were the subjects of this study. Age and sex-matched normal healthy individuals were included as controls. Plasma and salivary glucose levels were estimated by spectrophotometric method. Results: We observed significantly higher glucose levels in plasma and saliva, in diabetic patients with complications, in comparison to those without complications, and normal healthy controls. There was significant positive correlation between salivary glucose and plasma glucose among all the subjects of the study. Non-linear regression analysis shows exponential relationship between plasma and salivary glucose. Conclusion: Salivary glucose analysis offers noninvasive, sensitive method for assessment of severity of diabetic complications with suitability for repeated sampling. Further studies with larger sample size need to be taken up to establish salivary glucose as a marker of diabetes mellitus.
Authors and Affiliations
Dipti KH, Maitreyee DS, Shivashankara AR, Avinash SS, Malathi M5
Keywords
Related Articles
- EP ID EP242637
- DOI -
- Views 99
- Downloads 0
Is Placental Growth Factor an angiogenic marker in type 2 diabetes mellitus?
Introduction: Type 2 diabetes mellitus (T2DM) known by vascular complications due to abnormal angiogenesis leading to micro and macro vascular complications. PlGF a close homolog of VEGF, shares receptors with VEGF, and...
Levels of serum Gamma Glutamyl Transferase (GGT), high sensitivity C-Reactive Protein (hsCRP) in Myocardial Infarction (MI)-A case control study
Objectives: Acute myocardial infarction (AMI) is a major public health problem among non-communicable diseases in developing countries. Inflammation plays very important role in AMI. Gamma Glutamyl Transfersae (GGT) has...
Serum progesterone in first trimester of normal pregnancy
Appraisal of Oxidative Stress Markers, Vitamin E and their Correlation with Blood Pressure in Preeclampsia: A Case Control Study
Background and Objectives: Preeclampsia (PE), a hypertensive disorder unique to pregnancy and contributes to majority of maternal and perinatal morbidity and mortality. The triggering event in preeclampsia is postulated...
Lipid profile in hypertensive patients under diuretic therapy
Hypertension is a major health hazard of present day life and is a leading cause of global burden of disease. There is close association of hypertensive patient with dislipidemia. Low dose thiazide diuretics are used as...