A correlative study of salivary and plasma glucose levels in type 2 diabetic patients with and without complications
Journal Title: International Journal of Clinical Biochemistry and Research - Year 2016, Vol 3, Issue 2
Abstract
Introduction: There are contradictory reports on using salivary glucose in diagnosis of diabetes mellitus. This study has made an attempt to estimate the salivary glucose levels in diabetic patients with and without complications and correlate them with plasma glucose as a marker of type 2 diabetes mellitus. Method: This was a Cross sectional observational study. Thirty eight type 2 diabetic patients without complications and thirty eight type 2 diabetic patients with either microvascular or macrovascular complications were the subjects of this study. Age and sex-matched normal healthy individuals were included as controls. Plasma and salivary glucose levels were estimated by spectrophotometric method. Results: We observed significantly higher glucose levels in plasma and saliva, in diabetic patients with complications, in comparison to those without complications, and normal healthy controls. There was significant positive correlation between salivary glucose and plasma glucose among all the subjects of the study. Non-linear regression analysis shows exponential relationship between plasma and salivary glucose. Conclusion: Salivary glucose analysis offers noninvasive, sensitive method for assessment of severity of diabetic complications with suitability for repeated sampling. Further studies with larger sample size need to be taken up to establish salivary glucose as a marker of diabetes mellitus.
Authors and Affiliations
Dipti KH, Maitreyee DS, Shivashankara AR, Avinash SS, Malathi M5
Keywords
Related Articles
- EP ID EP242637
- DOI -
- Views 87
- Downloads 0
Relationship between ischemia modified albumin and lipid profile in type 2 diabetes mellitus
Introduction Ischemia modified albumin IMA is new biomarker of oxidative stress and ischemia IMA being increased in Diabetes Mellitus has been described in many studies Diabetes Mellitus DM a metabolic disorder is charac...
Estimation of various fractions of bilirubin in cases of neonatal jaundice
Background & Objectives: Neonatal jaundice causes yellow discoloration of the skin and sclera of the infants, caused by the accumulation of bilirubin in the skin and the mucous membrane. Before discharge the newborn shou...
Assessing the utility of serum Cholinesterase, Lactate dehydrogenase and Albumin/Globulin ratio in differentiating liver diseases
Introduction: Variety of liver diseases including alcoholic liver disease (ALD) is responsible for liver related morbidity and mortality in India. Distinguishing ALD from non-alcoholic steatohepatitis (NASH) and viral he...
Occupational lead exposure and its effect on human liver functions
Introduction: A Comparative study of persons working in lead based industries and non-lead based industries were undertaken to evaluate the effect of lead on liver function tests. This study was done to evaluate the ill...
Dendritic cells and vitamin D in dry eye disease
To study the role of dendritic cells and vitamin D in troublesome evaporative dry eye diseasesMaterials and Methods This is a cross sectional study which includes 108 patients having evaporative dry eye disease and 86 no...