A Correlative Study of Serum Ferritin Concentration and Glycated Hemoglobin in Type II Diabetes Mellitus
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2018, Vol 6, Issue 2
Abstract
Abstract: According to the Diabetes Atlas 2006 published by the International Diabetes Federation, the number of people with Diabetes in India currently around 40.9 million is expected to rise to 69.9 million by 2025. The present study has been undertaken to study the association between body iron store and diabetes mellitus by comparing serum ferritin and HbA1c levels. 70 diagnosed patients of Type II Diabetes Mellitus aged between 30 to 80 years were taken as cases and 70 apparently healthy age and gender matched individuals were taken as controls. Fasting and post prandial plasma glucose, serum ferritin and HbA1c levels were estimated by glucose oxidase-peroxidase method, solid phase direct sandwich ELISA method and Particle enhanced immune turbid metric method. Our study shows that the maximum number of cases between age groups of 41-50 years and mean ± SD of blood sugars (FBS and PPBS) serum ferritin and HbA1c were highly significant in study group in comparison to healthy control. Thus routine screening for serum ferritin should be carried out in person with impaired glucose tolerance to assess the body iron store and the risk of development of diabetes. There was a positive correlation between serum ferritin and FBS, PPBS, and HbA1c.
Authors and Affiliations
Dr. Priyanka Mishra, Dr. Biswajit Das, Dr. Geetika Mohan, Dr. Saurav Rai, Dr. Ujjwal Kumar, Dr. Ayaz Khurram Mallick
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