A Critical Analysis and Correlation Between Thoracoscopy Findings and Pleural Cytology in Malignant Diseases of Pleura
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2017, Vol 5, Issue 2
Abstract
Background: Primary or secondary malignant diseases of the pleura present variable thoracoscopy findings and so as cytology of pleural aspirations and histopathology. There are few studies correlating these two important modes of investigations in the accurate diagnosis of the malignant diseases of the pleura. Aim: Aim of the study was to correlate the thoracoscopy findings and cytology features of different malignant diseases of the pleural lesions and the pathological types of malignancy in malignant pleural effusion (MPE). Materials and Methods: A retrospective study was conducted by reviewing the medical records of 49 patients attending the Department of Medicine and Surgery with clinical signs and symptoms of MPE. The patients with confirmed MPE by pleural fluid cytology and tissue biopsy as well as macroscopic appearances of malignant pleural lesions on thoracoscopy were identified. Results: Metastatic adenocarcinoma was found in 27 (55.10%), malignant lymphoma in 9 (18.36%), malignant mesothelioma in 5 (10.20%), squamous cell carcinoma in 4 (8.16%), small cell carcinoma in 2 (4.08), and spindle cell tumor 2 (4.08%). Among the thoracoscopy findings nodular appearance was observed in 34 (69.38%), masses in 8 (16.32%), plaques in 3 (6.12%), and adhesions in 4 (8.165) of patients. Nodular finding was found in metastatic adenocarcinoma and malignant lymphoma 25 (76.47%) and 6 (66.66%), respectively. Conclusion: Thoracoscopy inspection would give the reasonable consistent macroscopic sign and can be correlated with cytology and biopsy findings of different malignant pleural lesions.
Authors and Affiliations
P G Anand Kumar, P A P Amjad
Keywords
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