A CROSS-SECTIONAL STUDY TO EVALUATE THE USEFULNESS OF ‘PRESSURE TO CORNEA INDEX’ IN PREDICTION OF PRIMARY OPEN ANGLE GLAUCOMA
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 1
Abstract
BACKGROUND The prevalence of glaucoma blindness is about 8% of global blindness and in India is about 4.4%. The Intraocular Pressure (IOP) is a single major modifiable risk factor in glaucoma. In order to integrate IOP and CCT as a single risk factor, a new index ‘Pressure-toCornea Index’ (PCI) was proposed. But studies regarding the fact that the increased values of PCI will be a risk factor for glaucoma are limited. This study attempts to describe the role of PCI as a predictive risk factor in clinical POAG. The aims and objectives of this study are to determine the PCI values in POAG, OHT and NTG and to determine whether PCI can be used as a predictive value in clinical Primary Open Angle Glaucoma (POAG). MATERIALS AND METHODS This observational, cross-sectional type of study was conducted over a period of six months, in 478 eyes of patients attending the outpatient at Govt. Rajaji Hospital, Madurai, who satisfied the inclusion-exclusion criteria. IOP estimation by GAT and CCT measurement by Ultrasound Pachymetry was done in all of them. After routine glaucoma evaluation, they were segregated as Group 1: Normotensives (374), Group 2: Ocular Hypertension (29), Group 3: Normal Tension Glaucoma (28) and Group 4: Primary Open Angle Glaucoma (47). Data collected were entered in Master Chart and statistical analysis was done using software IBM SSPS Ver 21.0 (Armonk, NY) by our statistician. The study groups without clinical POAG are Group 1 and Group 2 (mean PCI value of 92 and 117). The study groups with clinical POAG are Group 3 and Group 4 (mean PCI value of 134 and 171). This study demonstrates a significant correlation between PCI levels and glaucomatous changes in eyes. The PCI value may be also useful in the management of glaucoma for setting a target IOP. RESULTS The obtained ‘P’ value is < 0.001 which is statistically significant says that there is a difference in the IOP measurements and CCT measurements between the 4 groups (Normal, Ocular Hypertension, Normotensive Glaucoma and Primary Open Angle Glaucoma). CONCLUSION The value of PCI is significantly increased in glaucomatous (POAG and NTG) eyes. This emphasises that PCI can be used as a predictive index in development of glaucomatic changes in optic disc in the population.
Authors and Affiliations
Pandiyaraj Saravanasankar, Anbazhaghan Amudha, Srinivasan Muralikrishnan, Reethysreekumar Sruthi, Rajan Saranya, Muthusamy Charanya, Jothimani Deebalakshmi
Keywords
Related Articles
- EP ID EP283348
- DOI 10.14260/jemds/2018/12
- Views 86
- Downloads 0
RIGHT ILIAC FOSSA MASS- EVALUATION AND MANAGEMENT
BACKGROUND Mass in the Right Iliac Fossa (RIF) has since long exercised the minds of many surgeons. The various pathologies, multiple and varied modes of presentation of each disease entity, the difficulties encountered...
RISK FACTORS FOR DEVELOPMENT OF LYMPHEDEMA FOLLOWING BREAST CANCER TREATMENT: A RETROSPECTIVE STUDY
[b] OBJECTIVES[/b]: The aim and objective of this study is to identify the factors associated with secondary lymphedema after breast cancer treatment.[b] BACKGROUND:[/b] Lymphedema of the arm is a complication...
ANTIMICROBIAL SENSITIVITY OF GRAM-NEGATIVE BACTERIA WITH BETA LACTAM /BETA LACTAMASE INHIBITOR COMBINATION OF DRUGS IN COMPARISON TO OTHER ANTIBIOTICS IN TERTIARY CARE CENTER
BACKGROUND Objectives of the study were- 1. isolation and speciation of Gram-negative bacteria from urine, pus sample, wound swab, blood, tissue, BAL and other body fluids. 2. To identify bacteria most commonly isolated...
STRANGULATED LITTRE’S HERNIA: CASE REPORT AND REVIEW OF LITERATURE
Littre's hernia is uncommon clinical entity. We are presenting a case of Strangulated Littre's Hernia. A 19 years old male, came with pain and swelling in right inguinal region, which turned out to be an obstru...
COMPARATIVE ANALYSIS OF FATAL DELIBERATE SELF-HARM IN THE YEAR 2000 AND 2015- AN AUTOPSY STUDY
The state of Kerala has attained very high standards of health care at the National level, but the high rate of suicide is a major health problem which has to be tackled. The suicide rate in Kerala in 2014 (24.9 per 100,...