A cytohistopathological study to evaluate the diagnostic role of Fine-needle aspiration cytology (FNAC) in salivary gland lesions
Journal Title: Indian Journal of Pathology and Oncology - Year 2017, Vol 4, Issue 1
Abstract
Background & Objectives: FNAC is used as a preoperative diagnostic tool to differentiate between benign and malignant salivary glands (SGs) tumors. The aim of this study was to evaluate the sensitivity, specificity and diagnostic accuracy of the FNAC for SGs lesions. Methods: FNAC was carried out in 144 patients with various SGs lesions and classified. Out of 144 cases, only 59 cases were available for histopathological examination. FNAC diagnosis was compared with the final histological diagnosis; and then sensitivity, specificity and diagnostic accuracy of the FNAC for SGs lesions were calculated. Results: Parotid gland was involved in 54.86% cases, whereas submandibular and minor SGs were involved in 40.27% and 4.86% cases respectively. Non-neoplastic lesions were found in 50.7% cases, whereas benign and malignant lesions were found in 36.8% and 12.5% cases respectively. Submandibular gland was commonly (52.05%) involved in non –neoplastic lesions whereas in benign and malignant lesions, parotid gland was involved 64.15% and 77.78% cases respectively. Chronic sialadenitis (58.9%), pleomorphic adenoma (90.56%) and mucoepidermoid carcinoma (55.55%) were most common lesions among non–neoplastic, benign and malignant lesions respectively. Sensitivity, specificity and diagnostic accuracy of FNAC for neoplastic SGs lesions were 87.50%, 97.44% and 94.54% respectively. Interpretations & Conclusions: The high sensitivity, specificity and diagnostic accuracy of the FNAC indicates that it may serve as a good pre-operative diagnostic technique for SGs lesions. This study highlights the diagnostic value of FNAC in differentiating benign from malignant lesions which are useful in the planning of further management.
Authors and Affiliations
Rashmi Jain, Ankit Jain
Keywords
Related Articles
- EP ID EP311339
- DOI 10.18231/2394-6792.2017.0010
- Views 80
- Downloads 0
Cytomorphological study of mesenchymal spindle cell lesions of soft tissues by fine needle aspiration cytology
Introduction The objective of this study was to determine the scope of fine needle aspiration cytology FNAC in diagnosing mesenchymal spindle cell lesions of soft tissues Cytological findings of 52 cases were evaluatedMa...
Cytomorphological diversity in Hashimoto's Thyroiditis
Introduction: Hashimoto's thyroiditis is recognized as the next most common thyroid lesion after goiter, diagnosed on fine needle aspiration cytology. It is also considered as the foremost cause of hypothyroidism. Fine n...
The Bethesda system for reporting thyroid FNAC: A cytohistological correlation in a newly established institute
Introduction FNAC is an excellent modality for diagnosis of thyroid lesions because of its simplicity and cost effectiveness Since the introduction of The Bethesda System for Reporting Thyroid Cytopathology TBSRTC in 200...
Correlation of microvessel density with tumor type, tumor size, histological grade and lymph node status of breast carcinoma
Introduction Microvessel density is used in assessment of the angiogenesis a prognostic factor for many malignancies While it has extensively been studied in cancers of lung brain colon prostate as well as in melanoma bu...
Utility of C-Kit Expression by Immunohistochemistry as a Prognostic and Theranostic Marker in Colorectal Carcinoma
Objectives: Targeted therapy is now available for various carcinomas with growth factor receptor mutations. C-Kit, a tyrosine kinase receptor is overexpressed in many epithelial malignancies. The aim of this study is to...