A Demographic and Polysomnographic Investigation of Fatigue and Sleep Disorders in Patients with Multiple Sclerosis
Journal Title: Türk Uyku Tıbbı Dergisi - Year 2018, Vol 5, Issue 3
Abstract
Objective: To investigate fatigue and sleep disorders based on demographic, clinical and polysomnographic data and show their effects on the quality of life in multiple sclerosis (MS) patients. Materials and Methods: Thirty MS patients were enrolled in the study depending on the results of the polysomnography (PSG), Fatigue Severity scale, Epworth Sleepiness scale (ESS), Pittsburgh Sleep Quality Iindex, Beck Depression and Anxiety inventories. Patients, using (n=16) and non-using (n=14) interferon, were compared with each other in all parameters; ESS and PSG data were compared with a control group consisting of 19 healthy people. Short form-36 (SF-36) data were also compared with the society norms. Results: Central fatigue was observed in 86.7% of the patients. PSG data revealed that stage N2 sleep duration of those who did not use interferon was significantly longer than those who used it (p<0.001). According to the PSG, total sleep time, sleep efficiency, stage N3 and rapid eye movement time, mean respiratory disturbance index, sleep latency and the mean value of total leg movements were significantly higher in the patient group than in the control group (p<0.001). All parameters of SF-36 were significantly lower in patient group (p<0.001). The stage N3 sleep time length was found related with physical component summary of SF-36 (p<0.001). Conclusion: MS patients have high level of fatigue and additionally there are weighty disturbances in objective and subjective sleep parameters. Our findings were revealed that all the components of quality of life decreased significantly in these patients. Furthermore, our study showed that deep sleep duration was related with physical activity and emphasized the importance of sleep evaluation in MS patients.
Authors and Affiliations
Ali Özhan Sıvacı, Aylin Bican Demir, Ömer Faruk Turan, Özlem Taşkapılıoğlu, İbrahim Bora, Gökhan Ocakoğlu
Keywords
Related Articles
- EP ID EP421941
- DOI 10.4274/jtsm.70299
- Views 112
- Downloads 0
The Role of 13 Years Insomnia on Physiological Variables of an Active Man: A Case Report
The aim of this study was to monitor role of insomnia on some physiological variables in a man who had 13 years insomnia. In this case report, we had a case with 27 years old, 64 kg body mass index, 167 cm height and 13...
Effects of Overnight Sleep Deprivation on Appetite and Physical Performance in Elite Female Soccer Players
Objective: Sleep and awakening are a biological cycle that is affected by physiological function, light and darkness, work programs, and other activities. The vital role of sleep in body function and appetite is essentia...
Mothers’ Preferences for Safe Sleep in Newborns
Objective: It is extremely important to provide safe sleep for babies to be protected from sudden infant death syndrome. The aim of this study is to determine the preferences of newborn mothers to sleep their babies. Mat...
Restless Legs Syndrome in Patients with Epilepsy Under Levetiracetam Monotherapy
Objective: Restless Legs syndrome (RLS) is a frequent neurological disease. Levetiracetam (LEV) is an effective and broad-spectrum anticonvulsant drug. The aim of this study is to investigate the frequency of RLS in pati...
Relationship Between Sleep-related Violence and NREM Parasomnia: A Case Report
Parasomnia constitutes an important group among the situations that can lead to sleep-related violence scene. Parasomnia attacks are characterized by complex motor behaviors of various degrees, violent behaviors may resu...