A DESCRIPTIVE STUDY OF MRI IN ORAL CANCER PATIENTS AT A TERTIARY CARE HOSPITAL IN JAIPUR.
Journal Title: International Journal of Medical Science and Diagnosis Research (IJMSDR) - Year 2018, Vol 2, Issue 5
Abstract
Aim: To describe the observations of MRI in oral cancer patients as per Tumor size, Depth of tumor invasion, Bone involvement and T-staging assuming histopathology as gold standard. Material & methods: 70 patients with biopsy proven oral cancer with clinical stage at or below T4a were included in this hospital based descriptive type of observational study. All patient underwent clinical and MRI examination. MRI was performed on PHILIPS INGENIA 3 TESLA MRI. Images were interpreted as per tumor size, depth of tumor invasion, bone involvement and the tumor was staged for size (T) under TNM staging criteria of carcinoma oral cavity. All patients underwent surgery and the final diagnosis was made by histopathology. Statistical analysis was applied to find out the Sensitivity, Specificity, Accuracy, PPV and NPV of MRI. Agreement of association was inferred by kappa statistics. Correlation was inferred by Pearson’s Correlation coefficient. P-value < 0.05 was taken as significant. Results: Accuracy of MRI for T- staging in oral cancer patients was 82.85%. Kappa value for MRI data was 0.75. Average depth of invasion calculated on MRI was 8.48mm and by histopathology was 6.90mm.Pearsons correlation coefficient was 0.988. Shrinkage factor was 0.81. Sensitivity, specificity, accuracy, PPV and NPV of MRI in predicting bone invasion was 92.3%, 90.90%, 91.42%, 85.71% and 95.23% respectively. Conclusion: MRI tumor staging helps to plan appropriate therapy. Depth of invasion in oral malignancies can be measured reliably on MRI which helps in predicting cervical lymph nodal metastasis which can be used as an important supportive tool in deciding type of neck dissection and prognosis of patient. Keywords: Depth of tumor invasion, Oral Cancer, T-Stage.
Authors and Affiliations
Himanshu Sharma
Keywords
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