A descriptive study to assess the drug sensitivity pattern to antitubercular drugs in patients visiting department of respiratory medicine at a tertiary care hospital at Western Maharashtra
Journal Title: The Journal of Community Health Management - Year 2018, Vol 5, Issue 2
Abstract
ObjectiveIntroduction Tuberculosis is a overwhelming public health worry in India The Indian Subcontinent accounts for about 25 of the TB burden worldwide Across the world India has the highest burden of both TB and MDRTB The aim of this study was to study the resistance pattern of Mycobacterium Tuberculosis to first and second line antiTB drugs among specimens from a hospital in Tertiary Care Hospital in Western MaharashtraMaterials and Method This record based study was conducted at Tertiary Care Hospital in Western Maharashtrafrom January 2017 Records of Sputum from 2013 to 2017 were obtained from patients with suspected TB Drugsensitivity testing was performed by the Mycobacteria Growth Indicator Tube MGIT method Sensitivity to First line and second line drugs and Quinolones were testedResults Among 734 patients 701955 were males and 3345 were females Analysis of our Study result showed that 217 of patients were monodrug resistant Out of 734 isolates 56 762 showed multidrug resistance resistance to INH and RIF at least and 33 out of 734 45 whereas 39 56 out of the 734 samples showed XDR ConclusionThis study confirms that drug resistance including MDR observed against all firstline TB drugs was a real threat in the management of TB infection The patterns of resistance in this study will assist clinicians in providing the right treatment regimen to TB patients and bring about an improvement in their clinical conditionKeywords Pulmonary Tuberculosis Drug resistance
Authors and Affiliations
HS Sndhu, Shishir Jain, Ashish Bahal, Ayyappa G
Keywords
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- EP ID EP486906
- DOI 10.18231/2394-2738.2018.0024
- Views 108
- Downloads 0
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