A Detailed Study of Severity of Eosinophilia and its Relation With Number of Hookworms in Duodenum in Patients With Hookworm Infection Found While Doing Endoscopy
Journal Title: IJAR-Indian Journal of Applied Research - Year 2016, Vol 6, Issue 7
Abstract
Objective: Eosinophilia occurs very commonly in hookworm infection. Hence a detailed study was done to know about the severity of eosinophilia and its relation with number of hookworms in duodenum in patients with hookworm infection found while doing upper gastro intestinal endoscopy. Methods: A study of 1259 patients who had undergone upper gastro-intestinal endoscopy for a period of 5 years from May 2009 to April 2014 was carried out. In each of these 1259 patients,the first and second part of duodenum were carefully examined to find out the presence of single or multiple hookworms. In all the patients found to have hookworms in duodenum,investigations were done to know about the presence or absence of eosinophilia and the presence of severe eosinophilia. The results were found as given below. Results: Out of these 1259 patients, 14 patients found to have hookworms in duodenum were taken into consideration for our study. Out of these14 patients, as many as 10 patients with hookworms in duodenum were found to have eosinophilia [71%]. Severe eosinophilia was found in 4 out of 10 patients with eosinophilia(40%). The remaining 6 out of 10 patients had only mild eosinophilia . But 4 patients with hookworms in duodenum did not have any eosinophilia. All the 4 patients with severe eosinophilia are associated with multiple hookworms in duodenum. But majority of the patients without eosinophilia and with mild eosinophilia are associated with only single hookworm in duodenum. Conclusion: Hence, majority of the patients without eosinophilia and with mild eosinophilia are associated with only single hookworm in duodenum. But all the 4 patients with severe eosinophilia are associated with multiple hookworms in duodenum. Hence, severity of eosinophilia is directly proportional to the number of hookworms in duodenum
Authors and Affiliations
Govindarajalu Ganesan
Keywords
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