A Drug Utilisation Study of Antihyperglycaemic Agents in a Rural Tertiary Care Hospital
Journal Title: International Journal of Medical and Dental Sciences - Year 2017, Vol 6, Issue 1
Abstract
Background: Diabetes mellitus is an emerging non communicable, life style disease. The aim was to evaluate the drug utilization pattern of anti-diabetic drugs in diabetic outpatients and monitor the adverse drug reactions (ADRs) associated with anti-diabetic therapy. Materials and methods: A prospective observational study was carried out in adult diabetic patients from the Department of General Medicine of a rural tertiary care hospital in October 2013- December 2014 after obtaining written informed consent from the patient and approval from institutional ethics committee. Demographic data, drug utilization pattern, cost of the antidiabetic drugs along with defined daily dose was calculated. ADRs due to anti-diabetic drugs were summarized. Results: A total of 450 patients were enrolled in the study of which there was male preponderance and majority belong to geriatric age. The most common comorbidity was hypertension. Insulin was most commonly prescribed drug during hospital stay and metformin at the time of discharge. Of the combination therapy dual therapy of metformin and glimipiride was most preferred. The total antihyperglycaemic drug consumption was 15.65 DDD/100 bed days. 67 ADR were reported of which the most common was hypoglycaemia. Conclusions: The study showed insulin and metformin were the most commonly used drugs. The prescribing trend also appears to be moving towards combination therapy particularly two drug therapies. The most commonly reported ADR was hypoglycaemia.
Nutritional Status of Rural Govt. Primary School Children in Khammam District, Andhra Pradesh, India
Background: Rural school children are more vulnerable victims of undernutrition and its consequences. On that ground, rural govt. primary school children were examined on the basis of height, weight and few background va...
Study on combined cortical thickness, total diameter of clavicle and cortical index of adult human clavicle in north Indians
Introduction: Clavicle has a complex bone structure, is variable in shape and exhibits dramatic variations both in curvatures and cross sectional geometry. Clavicle has been globally studied for purpose of generating a s...
Pathobiological Characteristics of Intestinal and Diffuse-Type of Gastric Carcinoma-Retrospective Study of Gastric Cancers
Background: Gastric carcinomas have various pathological features. Based on patterns of growth and invasiveness, however, they fall into two types: diffuse type and intestinal type. These two types of carcinoma appear to...
Pulmonary Nocardiosis Mimicking Tuberculosis
Pulmonary nocardiosis is an infrequent and severe infection due to Nocardia species, microorganisms that may behave both as opportunists and as primary pathogens. Diagnosis of pulmonary nocardiosis is frequently delayed...
Knowledge, attitude and practice towards exclusive breastfeeding among lactating mothers: descriptive cross sectional study
Background: Exclusive breastfeeding (EBF) is the best nutrition for children during the first six months of life. However EBF remains a challenge. Objective: The aim of the study was to assess Knowledge, Attitude and Pra...