A Facile One-pot Synthesis of New Pyrazolopyrimidines and Pyrazolo Pyridines Derivatives

Journal Title: JOURNAL OF ADVANCES IN CHEMISTRY - Year 2014, Vol 8, Issue 1

Abstract

A Simple Facile One-pot reaction, novel and efficient rout for the synthesis of substituted pyrazolo [3, 4-d] pyrimidines, and pyrazolo [3, 4-b] pyridines, results from reaction of substituted-5-amino-4-cyanopyrazoles with malononitrile and diethylmalonate respectively. The structures of the products and conceivable mechanisms are discussed. The antibacterial activity of some new synthesized compounds was evaluated and seemed to be significant.

Authors and Affiliations

Hatem Abdel Moniem Ahmed

Keywords

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  • EP ID EP652677
  • DOI 10.24297/jac.v8i1.6789
  • Views 164
  • Downloads 0

How To Cite

Hatem Abdel Moniem Ahmed (2014). A Facile One-pot Synthesis of New Pyrazolopyrimidines and Pyrazolo Pyridines Derivatives. JOURNAL OF ADVANCES IN CHEMISTRY, 8(1), 1533-1538. https://europub.co.uk/articles/-A-652677