A Facile Synthesis of Pyrimidoquinazoline Derivatives
Journal Title: JOURNAL OF ADVANCES IN CHEMISTRY - Year 2014, Vol 7, Issue 3
Abstract
A series of pyrimidoquinazoline are prepared via the reaction of ethyl 2,2-dicyano-1-arylvinylcarbamate derivatives 1a-b with methyl 2-aminobenzoate, 1-(2-aminophenyl)ethanone and 2-aminobenzonitrile. The reactivity of compounds 1a-b toward 3-amino-4,6-diphénylnicotinonitrile are studied. The structures of the synthesized compounds are elucidated by X-ray diffraction, IR spectroscopy and nuclear magnetic resonance.Â
Authors and Affiliations
Mona Boukthir, Fathi Zribi, Mohamed Belhouchet, Fakher Chabchoub
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