A Follow UP Observational Study of Collodion Babies from an Indian Tertiary Care Hospital
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2018, Vol 3, Issue 6
Abstract
Background and Aims: Collodion baby is a rare presentation in which child is born encased in a taut, parchment like membrane Materials and Methods: The study comprised of collodion neonates presenting to department of dermatology of Lady Hardinge Medical College and associated Kalawati Saran Children s Hospital, New Delhi over a period of one year. Relevant history, examination and investigations were recorded. The parents were counseled and reminded telephonically of periodic follow up. Results: The clinical spectrum of these documented patients is as under: Case 1: A 1 day old full term girl presented with collodion membrane, generalized erythema and ectropion with fissuring in flexures. Emollients were advised and the child is now a healthy toddler with mild form of non bullous ichthyosiform erythroderma. Case 2: A 3 day old preterm boy was referred to our hospital with collodion and severe ectropion with neonatal septicemia; the child expired at day 4 of life. Case 3: A 1 day old preterm boy, born of a consanguineous marriage, was born with collodion membrane, severe ectropion, eclabion and inability to suck .He expired after few hours of life. Case 4: A 1 day old preterm girl child born with collodion membrane, ectropion and eclabion was referred from a local hospital. She was treated with oral acitretin. The ectropion & eclabion resolved and scaling improved at 4 weeks. The child was lost to follow up. Case 5: A 1 day old full term male baby was born with collodion membrane and ectropion. Mother gave history of 3 male stillbirths. He was put on nutritional supplements and emollient care with gradual transition into non bullous ichthyosiform erythroderma. Conclusion: The study series of this rare phenomenon highlights the variable spectrum of collodion baby. Collodion baby is a rare entity with an incidence of 1 in 300, 00. 1 The term collodion baby refers to a clinical entity used for newborns who are encompassed by a tight, shiny, translucent and parchment paper like skin sheet called as collodion membrane, on the entire body surface which lasts for days to weeks.2 The shedding of collodion membrane starts within a day or two and is nearly complete by 4 weeks.3 The prognosis of collodion baby depends solely on the type of icthyosis which develops following the shedding of collodion membrane.4,5,6 We present a study of collodion babies and the subsequent course of their disease.
Authors and Affiliations
Dr Masarat Jabeen
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