A four year retrospective hospital based seroprevalence study of dengue infection in tertiary care hospital, Jaipur, Rajasthan
Journal Title: MedPulse -International Medical Journal - Year 2016, Vol 3, Issue 4
Abstract
Introduction: Dengue is one of the serious mosquitoe-borne viral infection affecting tropical and subtropical countries in the world. As Dengue has become endemic in India with outbreaks occurring almost every year, there is a need to assess the magnitude of Dengue virus infection in the state of Rajasthan. A surveillance based retrospective study was conducted for 4 years. The study analyzed Dengue seropositivity among patients with clinical suspicion of Dengue fever like illness at a tertiary care hospital of Jaipur, Rajasthan. Material and Methods: Serum samples from 48540 suspected Dengue cases were received in the clinical microbiology section of central laboratory of S.M.S. Hospital, Jaipur over a period of 4 years (2012-2015). The samples were subjected to Rapid Immunochromatographic assay with differential detection of IgM and IgG antibodies. Results: Among 48540 patients screened, 6.7% (3265) were Dengue specific IgM antibody positive cases. Maximum numbers of positive cases were observed in 2013 (12.13%). Majority (10.86%) of positive cases were detected in the month of October i.e post monsoon season. The most commonly affected age group was 16 to 35 yrs. Thrombocytopenia was observed in 59.05% of Dengue positive case. Conclusion: Diagnosis of Dengue by rapid method like immunochromatography along with platelet counts was found valuable. Our study highlights the need for continuous surveillance for early detection of impending outbreak to initiate timely preventive control
Authors and Affiliations
Manju Yadav, Rameshwari Bittu, Veena Balothia, Nitya Vyas, R K Maheshwari
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