A Histomorphological Study of Abnormal Uterine Bleeding

Journal Title: Indian Journal of Pathology: Research and Practice - Year 2017, Vol 6, Issue 3

Abstract

The study is a prospective study undertaken on endometrial curettings from clinically diagnosed cases of abnormal uterine bleeding (AUB). The objectives were to analyze the histomorhological patterns of endometrium in clinically diagnosed cases of AUB in different age groups in comparison with the other similar studies. Patients from all the age groups were included in the study and all types of pregnancy complications were excluded from the study. The endometrial biopsy material, fixed in 10% formalin was processed, sections were cut from blocks prepared from paraffin, stained with H&E and studied. A total of 100 endometrial biopsies from clinically diagnosed AUB patients were studied histopathologically. Out of these 46% were simple hyperplasia, 22% were proliferative endometrium, 9% were complex hyperplasia, 8%were secretory phase, disordered proliferative endometrium and endometrial polyp were 4% each, anovulatory endometrium and adenocarcinoma were 2% each, chronic endometritis , inadequate secretory phase and pillendometrium were 1% each. Majority of the patients in the present study were in the age groups of 4150yrs. Most common presenting complaint in the present study was menorrhagia. In conclusion it is observed that AUB is most common in perimenopausal age groups with histomorphological pattern of simple hyperplasia, followed by normal proliferative pattern, secretory pattern and endometrial carcinoma is seen in older age groups and most commonly presenting with post menopausal bleeding. Histopathological findings in the endometrial biopsies of these patients help to detect & differentiate between functional causes and organic lesions there by facilitating appropriate patient management.

Authors and Affiliations

Karumbaiah K. P.

Keywords

Related Articles

Insights of Uterine Leiomyomas

Background: Fibroid is the commonest tumor of the reproductive tract and frequently encountered problem in gynecological practice. Aim and objectives: To observe the frequency of uterine leiomyoma in relation to age, par...

Histopathological Spectrum of Nasal Polyps: A Sixteen Months Study

Introduction: Nasal polyps are polypoidal masses arising from the nasal cavity and paranasal sinuses. They can be non-neoplastic, can have an infective etiology, or they can be benign or malignant. Aim of the Study: To s...

Clinicopathological Study of Benign Skin Tumors

Background: Benign skin tumors constitute a small part of the surgical specimens. However, histopathologically, there is a wide variety of benign skin tumors. Aim and Objectives: To study the histopathology of benign sk...

Histomorphological Evaluation of Lichen Planus in a Rural Population: A Retrospective Hospital Based Study.

Context: Lichen planus is a common inflammatory disorder,that commonly affects skin,nail,mucous membrane and hair. The morphology, distribution and colour of lichen planus is usually variable clinically. Aim: The aim o...

Peripheral Smear, an Important Diagnostic Tool in the Diagnosis and Monitoring of Disease Activity in Dengue Fever, in Resource Limited Settings

Background: Dengue fever is the most common arbovirus infection in the world. Clinical manifestation range from fever to dengue shock syndrome (DSS). Clinical diagnosis can be difficult, as its presenting signs and sympt...

Download PDF file
  • EP ID EP466343
  • DOI 10.21088/ijprp.2278.148X.6317.10
  • Views 108
  • Downloads 0

How To Cite

Karumbaiah K. P. (2017). A Histomorphological Study of Abnormal Uterine Bleeding. Indian Journal of Pathology: Research and Practice, 6(3), 563-568. https://europub.co.uk/articles/-A-466343