A Logarithmic Formula to Describe the Relationship between the Increased Radiosensitivity at Low Doses and the Survival at 2 Gray
Journal Title: Sultan Qaboos University Medical Journal - Year 2013, Vol 13, Issue 4
Abstract
Objectives: Intrinsic radiosensitivity at doses used in radiotherapy is linked to hypersensitivity (HRS) and increased radio resistance (IRR) at low doses. Te aim of this study was to explore this relationship. Methods: Survival curves for 18 human tumour cell lines were analysed, using two models to ft the data points in order to extract the necessary parameters relevant for this study. Results: Te IRR ratio α s /α r versus the survival at 2 gray (Gy) can be described by a logarithmic relation which leads to a series of straight lines. Conclusion: Te relationship obtained implies that there is a direct link between HRS/IRR and survival at clinically relevant doses of 2 Gy.
Authors and Affiliations
Faika A. Azooz| Department of Physics, College of Education, University of Mosul, Mosul, Ninevah, Iraq, Suzan K. Hashim| Department of Physics, College of Education, University of Mosul, Mosul, Ninevah, Iraq
Keywords
Related Articles
- EP ID EP14403
- DOI -
- Views 343
- Downloads 10
Nasopharyngeal Salivary Gland Anlage Tumour A rare cause of neonatal respiratory distress
A salivary gland anlage tumour (SGAT) is a very rare type of benign tumour that usually presents in early infancy with respiratory distress which is exacerbated upon feeding. We report a full-term male neonate who was...
Syringocystadenoma Papilliferum of the Upper Lip
Syringocystadenoma papilliferum (SCAP) is a rare skin tumour believed to arise from the apocrine or eccrine sweat glands. It appears predominantly in childhood, usually at birth. It is exceedingly rare for it to appear...
Relatives’ Advice and Health Care-Seeking Behaviour in Oman
It has been well established that pathways to care are considerably modifed by local, social and psychological characteristics as well as the doctor-patient relationship. Scant attention has been paid to the role of fam...
Prevalence of Uncontrolled Hypertension in Primary Care Settings in Al Seeb Wilayat, Oman
Objectives: Tis study aimed to estimate the prevalence of uncontrolled hypertension (HTN) among Omani hypertensive patients, on treatment and under primary health care (PHC) follow-up in Al Seeb Wilayat, Oman. Socio-de...
Analysis of Tobacco-Specifc Nitrosamines in the Common Smokeless Tobacco Afzal in Oman
Objectives: Tere is a lack of awareness regarding the carcinogenicity of Afzal, an illegal smokeless tobacco product (STP) widely used among the Omani youth. Previous research has shown that certain types of tobacco-sp...