Common SPINK-1 mutations do not predispose to the development of non-alcoholic fatty liver disease

Background: Non-alcoholic fatty liver disease (NAFLD) is common in obese and diabetics. Serine protease inhibitor Kazal-1 (SPINK-1) protein is highly expressed in the liver and adipose tissue of diabetic and obese sugges...

Defining renal failure in cirrhosis –Acute kidney injury classification or traditional criteria?

Efficacy of telaprevir-based therapy in stable liver transplant patients with chronic genotype 1 hepatitis C

Background and rationale. The REPLACE study (NCT01571583) investigated telaprevir-based triple therapy in patients whohave recurrent genotype 1 hepatitis C virus (HCV) infection following liver transplantation and are o...

Hepatic Echinococcosis with Thoracic Involvement. Clinical Characteristics of a Prospective Series of Cases

Abstract Introduction. Thoracic involvement (TIHE) is one of the evolutionary complications of hepatic echinococcosis (HE). Aim. The aim of this study was to describe the clinical characteristics and postoperative morbid...

G308A polymorphism of TNF-alpha gene is associated with insulin resistance and histological changes in non alcoholic fatty liver disease patien

Some studies have pointed to a role of TNF-alpha in pathogenesis of non alcoholic fatty liver disease (NAFLD). The aim of our study was to investigate the influence of G308A polymorphism TNF alpha gene on the histologica...