A newborn with diabetic ketoacidosis and thalassemia major: A rare case
Journal Title: Dicle Tıp Dergisi - Year 2012, Vol 39, Issue 1
Abstract
Diabetic ketoacidosis is a systemic situation caused by absolute insulin deficiency and characterized by hyperglycemia, ketonemia, acidemia, glycosuria and ketonuria. Thalassemia Major is a very serious hereditary blood disorder due to low levels or absence of “beta globulin” chain, characterized by requiring a blood transfusion from 3-4. month of life due to the relatively short life of red cells. We, herein presented a rare case of 20 day-old newborn with anemia, hyperglycemia, vomiting, acidosis being diagnosed as thalassemia major that required blood transfusion in the early period of life and diabetic ketoacidosis without ketonuria who born from 24 year old father carrier of thalassemia and 23-year-old mother with carrier of thalassemia and gestational diabetes. The case was presented in order to emphasize that diabetic ketoacidosis can occur in newborns without ketonuria and thalassemia major may cause anemia in the early period of life due to hyperglycemia and acidosis
Authors and Affiliations
İlyas Yolbaş, Velat Şen, Hasan Balık, Selvi Kelekçi, Kenan Haspolat, Ünal Uluca, İlhan Tan
Keywords
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